Results 71 to 80 of about 454,529 (335)
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Spatio-temporal distribution of off-shore ships in the Pars Special Economic Energy Zone based on satellite imagery [PDF]
Environmental Resources Research, 2019 Special Economic Zones (SEZs) are areas controlled by specific legislations so as toattain economic prosperity. These zones are commonly established and controlled bygovernment officials and are primarily characterized by growing population and ...
Qadir Ashournejad +3 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Online Academic Journal of Information TechnologyBu çalışma, görsel sanatlar eğitimi ve teknoloji entegrasyonunu farklı açılardan ele alan akademik çalışmaların bulgularını bir araya getirerek bu alandaki mevcut durumu değerlendirmeyi ve gelecekteki araştırmalara ışık tutmayı amaçlamaktadır.
Hamit Gış, Arzu Deveci Topal
doaj +1 more source
“GIS works!”—But why, how, and for whom? Findings from a systematic review
Trans. GIS, 2020 This article presents the findings from systematically reviewing 26 empirical research studies published from 2005 to 2014 on the use of GIS for learning and teaching.
U. Schulze
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Oil pipeline route optimization using multi-criteria analysis in GIS [PDF]
علوم محیطی, 2017 Introduction: According to distribution requirements and the broad distance between production and consumption centres in Iran, linear infrastructure development plays an important role and should be considered as a vital necessity.
shahram Mohammadi +4 more
doaj
A MCDM Based on Goal Programming and GIS-Based Risk Assessment for the Evaluation of Educational Locations in Conflict Areas [PDF]
, 2021 Jamil Hallak, Elifcan Göçmen
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source