Results 81 to 90 of about 378,633 (284)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Geographic Information System (GIS) Tutorial
, 2023 The MIT GIS Services Group at the MIT Libraries hosts a number of tutorial workshops throughout the year. This resource gathers together some of those introductory workshop materials designed to accustom GIS novices to the various available software ...
MIT GIS Services Group
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Improving the accuracy of livestock distribution estimates through spatial interpolation
Geospatial Health, 2012 Animal distribution maps serve many purposes such as estimating transmission risk of zoonotic pathogens to both animals and humans. The reliability and usability of such maps is highly dependent on the quality of the input data. However, decisions on how
Ward Bryssinckx +6 more
doaj +1 more source
Journal of Maps, 2020 The 2019 Geomorphological Field Camp at San Domino Island (Tremiti Islands, Southern Adriatic Sea) is the result of geological and geomorphological field work activities carried out by a group of students attending the Geomorphological field mapping ...
Marcello Buccolini +31 more
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
3D-GIS Integration for Virtual NewcastleGateshead [PDF]
, 2010 Tools and technologies are developing to help the simulation of our cities for visualization, analytical and information modeling purposes. In this paper the authors, as well as evaluating different applications for 3D GIS solutions, are investigating ...
Horne, Margaret, Thompson, Emine Mine
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Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
GeoTopo-Net: A GIS-Based Framework for Automated Topology Recognition and Equipment Grouping in Power Distribution Networks [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information SciencesPower distribution networks are critical infrastructure, yet their effective management is limited by the lack of standardized, topologically coherent equipment representations.
O. Deniz, E. R. Tekin, S. N. Arslan
doaj +1 more source
Usability engineering for GIS: learning from a screenshot [PDF]
, 2007 In this paper, the focus is on the concept of Usability Engineering for GIS – a set of techniques and methods that are especially suitable for evaluating the usability of GIS applications – which can be deployed as part of the development process.
Zafiri, A.F. +4 more
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