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Why precision oncology works: lessons from gastrointestinal stromal tumours [PDF]

open access: yesExploration of Targeted Anti-tumor Therapy
Gastrointestinal stromal tumours (GISTs) are the clearest solid-tumour model of precision oncology because diagnosis, prognosis, and treatment are strongly shaped by molecular genotype. The discovery of activating mutations in KIT proto-oncogene receptor
Si Ying Adelina Ho   +4 more
doaj   +2 more sources

A Rare Case of Gastrointestinal Stromal Tumor of the Abdominal Wall [PDF]

open access: yesModern Medicine, 2022
Gastrointestinal stromal tumors (GIST) are rarely encountered in medical practice, developing with predilection in people over 40 years old. Their starting point is found in the digestive tract, and can appear anywhere along it.
Florin BOBIRCA   +6 more
doaj   +1 more source

Gist ileal

open access: yesBrazilian Journal of Health Review, 2022
Introdução: Os tumores estromais gastrointestinais (GISTs) são os tumores mesenquimatosos mais comuns no trato gastrointestinal, podendo acometer qualquer parte do trato gastrointestinal, embora sejam mais frequentemente diagnosticados no estômago. Apresentação do caso:  Paciente do sexo masculino, 63 anos de idade, com uma massa abdominal localizada ...
Sander, Renata Cury   +21 more
openaire   +2 more sources

W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state

open access: yesCommunications Biology, 2023
Human ATP-binding cassette transporter subfamily B6 (ABCB6) is a mitochondrial ATP-driven pump that translocates porphyrins from the cytoplasm into mitochondria for heme biosynthesis.
Sang Soo Lee   +6 more
doaj   +1 more source

18F-FDG PET/CT “hepatic superscan” in incomplete Carney’s triad [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2020
Introduction. Carney triad is a rare non-hereditary condition characterized by gastrointestinal stromal tumors – intramural mesenchymal tumors of the gastrointestinal tract with neuronal or neural crest cell origin, pulmonary chondromas, and extra ...
Zivgarević Ljiljana   +2 more
doaj   +1 more source

Varied Clinical Presentations of Small Bowel Malignancies Posing Diagnostic Uncertainty and their Management [PDF]

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2019
Introduction: Incidence of small bowel malignancy is lower compared to other parts of gastrointestinal tract for various reasons explained in literature.
Harish Kumar Hanumappa   +4 more
doaj   +1 more source

Role of Multidetector CT Imaging in the Risk Stratification of Gastrointestinal Stromal Tumors (GISTs)–A Retrospective Analysis

open access: yesJournal of Gastrointestinal and Abdominal Radiology, 2021
Background Gastrointestinal stromal tumors (GISTs) are the most common gastrointestinal mesenchymal neoplasms which can arise from any part of the gastrointestinal tract (GIT) or an extraintestinal location.
Geena Benjamin   +6 more
doaj   +1 more source

GIST-IT [PDF]

open access: yesProceedings of the workshop on Human Language Technology and Knowledge Management -, 2001
We present a system for the automatic extraction of salient information from email messages, thus providing the gist of their meaning. Dealing with email raises several challenges that we address in this paper: heterogeneous data in terms of length and topic.
Evelyne Tzoukermann   +2 more
openaire   +1 more source

Extra-Gastrointestinal Stromal Tumor (EGIST) in the Pelvis Mimicking Retroperitoneal Sarcoma

open access: yesThe Surgery Journal, 2022
Extra-gastrointestinal stromal tumors (EGISTs) are rare mesenchymal tumors accounting for less than 1% of total gastrointestinal tumors. They tend to be aggressive and have a poor prognosis.
Etienne El-Helou   +8 more
doaj   +1 more source

A rare presentation of gastrointestinal stromal tumor arising from a meckel's diverticulum: A case report

open access: yesJournal of Family Medicine and Primary Care, 2022
The most common congenital gastrointestinal tract abnormality is Meckel's diverticulum, affecting 1% to 2% of the population. Meckel's diverticulum can sometimes house a gastrointestinal stromal tumor (GIST), which is a rare malignant tumor.
Aditya Patel   +2 more
doaj   +1 more source

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