Results 21 to 30 of about 116,518 (256)

Limited Resection in Duodenal Malignancy: A single Center Experience [PDF]

open access: yesInternational Journal of Medical Arts
Background: Pancreas-sparing duodenectomy [PSD] has come a long way since its conception in 1990s. Since then, less than 200 cases have been published.Aim of the study: This study designed to share the outcomes of 3 Lynch Syndrome [LS], 2 ...
Mohammed Mamdouh Asar.   +1 more
doaj   +1 more source

Emerging Data on the Safety and Efficacy of Ripretinib for the Treatment of Gastrointestinal Stromal Tumors

open access: yesClinical and Experimental Gastroenterology, 2023
Prapassorn Thirasastr, Neeta Somaiah Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence: Neeta Somaiah, Department of Sarcoma Medical Oncology, The University of Texas MD Anderson ...
Thirasastr P, Somaiah N
doaj  

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Fusion yield enhancement via secondary beam-target reactions in laser-cluster experiments

open access: yesScientific Reports
Laser-cluster fusion offers a unique compact platform for studying nuclear reactions in the sub-100 keV regime. Here we report the first experimental demonstration of secondary beam-target DD fusion reactions in laser-cluster fusion experiments by ...
Jun Sim   +7 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Cryo-EM structure of cadmium-bound human ABCB6

open access: yesCommunications Biology
ATP-binding cassette transporter B6 (ABCB6), a protein essential for heme biosynthesis in mitochondria, also functions as a heavy metal efflux pump. Here, we present cryo-electron microscopy structures of human ABCB6 bound to a cadmium Cd(II) ion in the ...
Seung Hun Choi   +5 more
doaj   +1 more source

Gastrointestinal stromal tumors: a focus on the impact of interstitial cells of Cajal in disease development

open access: yesJournal of Mind and Medical Sciences
Introduction. Interstitial Cells of Cajal (ICCs) play a critical role in the regulation of gastrointestinal motility and have been implicated in various functional gastrointestinal disorders.
Petru Radu   +14 more
doaj   +1 more source

Evaluation of the gastrointestinal stromal tumors for clinical features, histopathological findings and prognostic criteria: A case-control study

open access: yesİstanbul Kuzey Klinikleri, 2020
OBJECTIVE: In this study, we reviewed GISTs with all morphological and immunohistochemical findings and assessed the prognostic parameters of these tumors.
Tolga Canbak   +3 more
doaj   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom   +15 more
wiley   +1 more source

Enhanced homeostatic sleep response and decreased neurodegenerative proteins in cereblon knock-out mice

open access: yesCommunications Biology
Energy homeostasis and sleep have a bidirectional relationship. Cereblon (CRBN) regulates energy levels by ubiquitinating the AMP-activated protein kinase(AMPK), an energy sensor. However, whether CRBN participates in sleep is unclear.
Jun-Hyung Jung   +10 more
doaj   +1 more source

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