Results 151 to 160 of about 112,663 (257)

Targeting the Unmet Need in Gastrointestinal Stromal Tumors: A Contemporary Review of Investigational Clinical Trials and Therapeutic Landscape. [PDF]

Pharmaceuticals (Basel)
Belančić A, Prejac J, Golčić M, Adžić G, Katić A, Kocić L, Kovač Peić A, Librenjak N, Belev B, Mikolašević I, Pleština S.   +10 more
europepmc   +1 more source

A GIST or not a GIST? That is the question.

Annals of gastroenterology
Nikolaos, Chrysanthos, Vasiliki, Xiromeritou, Nikolaos, Sfougatakis, Ioannis, Karoumpalis   +3 more
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Case Report: A liver metastasis 24 years after resection of a very low-risk jejunal gastrointestinal stromal tumor. [PDF]

Front Oncol
Yin X, Yang H, Sun L, Yin Y, Zhang B.
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Laparoscopic Resection of Incidentally Detected Early-Stage Synchronous Duodenal and Jejunal Gastrointestinal Stromal Tumors in a Patient with Neurofibromatosis Type 1. [PDF]

Surg Case Rep
Urabe K, Oshita A, Takei D, Tanimoto M, Ojima Y, Kagawa T, Inoue M, Kitamura S, Hanada K, Yonehara S, Takahashi S, Tanimoto Y.   +11 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Targeting tumor dormancy: the next frontier in gastrointestinal stromal tumor therapy. [PDF]

Neoplasia
Wu S, Liu H, Yin Y, Li J, Zhang Z, Li W, Fu Y.   +6 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Multifocal Small Bowel Gastrointestinal Stromal Tumors and Concurrent Neuroendocrine Tumor in Neurofibromatosis Type 1. [PDF]

ACG Case Rep J
Thakkar B, Da Cunha T, Zanchelli P, Dharan M.   +3 more
europepmc   +1 more source