Results 161 to 170 of about 116,518 (256)

Updated Asian consensus guidelines for the diagnosis and management of gastrointestinal stromal tumor (2025). [PDF]

Gastric Cancer
Hirano H, Naito Y, Takahashi T, Hirota S, Kim KM, Ryu MH, Wang J, Cao H, Li J, Li CF, Yen CC, Yang HK, Jung HY, Yeh CN, Wang HP, Chen LT, Shen L, Kang YK, Nishida T.   +18 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

When Histology Is Unknown: Surgical Decision-Making in Small Bowel Tumors-From Preoperative Imaging to Intraoperative Findings: A Narrative Review. [PDF]

J Clin Med
Obleaga CV, Cazacu SM, Mirea CS, Mesina R, Pascu AM, Târtea GC, Florescu MM, Vasile DF, Florescu LM, Vasile I, Vere CC.   +10 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Gastrointestinal stromal tumor of the round ligament with synchronous colorectal adenocarcinoma and hepatic metastases: a unique case report. [PDF]

Int J Surg Case Rep
Derkaoui A, Deflaoui T, Aissi I, Guellil A, Jabi R, Bouziane M.   +5 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Precision oncology meets Generative AI: assessing large language models in multidisciplinary GIST tumor boards. [PDF]

BMC Cancer
Dehdab R, Herrmann J, Mankertz F, Ghibes P, Maalouf N, Werner S, Strohäker J, Benzler K, Zender L, Afat S, Nikolaou K, Deinzer CKW.   +11 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The prognosis of patients with gastrointestinal stromal tumors harboring the KIT exon 11 mutation: a retrospective cohort study. [PDF]

J Gastrointest Oncol
Shou C, Yang W, Wang X, Zhang Q, Yu J, Liang T.   +5 more
europepmc   +1 more source