Results 161 to 170 of about 298,626 (342)

Management of GIST

Journal of Health Science and Medical Research (JHSMR), 2007
Gastrointestinal stromal tumor (GIST) is currently defined as a gastrointestinal tract mesenchymal tumor showing positive CD117 (c-kit protein). A GIST is the most common kind of mesenchymal tumor arising from the alimentary tract, and was previously ...
W Wanitsuwan, S Sunpaweravong
doaj  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Exploring how broad associative thought enhances scene gist perception

, 2020
Shira Baror, Moshe Bar, Elissa Aminoff
openalex   +1 more source

MicroRNA profiling in KIT and SDH mutated Gastrointestinal stromal tumor (GIST) [PDF]

, 2015
Gloria Ravegnini, Maria A. Pantaleo, Annalisa Astolfi, Guido Biasco, Patrizia Hrelia, Margherita Nannini, Sabrina Angelini   +6 more
openalex   +1 more source

Supplementary Fig. 3 from Antitumor Efficacy of the Novel KIT Inhibitor IDRX-42 (Formerly M4205) in Patient- and Cell Line–Derived Xenograft Models of Gastrointestinal Stromal Tumor (GIST) [PDF]

, 2023
Luna De Sutter, Agnieszka Woźniak, Jasper Verreet, Ulla Vanleeuw, Lore De Cock, Nina Linde, Christine Drechsler, Christina Esdar, Raf Sciot, Patrick Schöffski   +9 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

P-0055 Clinical Features and Treatment of Gastric Gist - our Experience

, 2012
Avdyl Krasniqi, Besnik Bicaj, Rifat Bajrami, Faton Hoxha, Agim Sharku, Astrit Hamza, Valon A. Zejnullahu, Fisnik Kurshumliu, Lumturije Gashi-Luci   +8 more
openalex   +1 more source

Enhanced formation of tertiary lymphoid structures shapes the anti-tumor microenvironment in gastrointestinal stromal tumors after imatinib targeted therapy. [PDF]

Theranostics
Tao P, Wang J, Fan P, Liu W, Lu W, Hu Y, Lu Q, Ma L, Tong H, Zhang Y.   +9 more
europepmc   +1 more source