Results 31 to 40 of about 298,626 (342)
Knowledge-rich Image Gist Understanding Beyond Literal Meaning
, 2018 We investigate the problem of understanding the message (gist) conveyed by images and their captions as found, for instance, on websites or news articles. To this end, we propose a methodology to capture the meaning of image-caption pairs on the basis of
Dietz, Laura +4 more
core +1 more source
Population-based SEER trend analysis of overall and cancer-specific survival in 5138 patients with gastrointestinal stromal tumor [PDF]
, 2015 Background: The objective of the present population-based analysis was to assess survival patterns in patients with resected and metastatic GIST. Methods: Patients with histologically proven GIST were extracted from the Surveillance, Epidemiology and ...
Cerny, Thomas +4 more
core +1 more source
Clinical and Experimental Gastroenterology, 2023 Prapassorn Thirasastr, Neeta Somaiah Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USACorrespondence: Neeta Somaiah, Department of Sarcoma Medical Oncology, The University of Texas MD Anderson ...
Thirasastr P, Somaiah N
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale +6 more
wiley +1 more source
Cryo-EM structure of cadmium-bound human ABCB6
Communications BiologyATP-binding cassette transporter B6 (ABCB6), a protein essential for heme biosynthesis in mitochondria, also functions as a heavy metal efflux pump. Here, we present cryo-electron microscopy structures of human ABCB6 bound to a cadmium Cd(II) ion in the ...
Seung Hun Choi +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein +3 more
wiley +1 more source
p53 Modulation as a Therapeutic Strategy in Gastrointestinal Stromal Tumors [PDF]
, 2012 The KIT-inhibitor imatinib mesylate (IM) has greatly improved the treatment of metastatic gastrointestinal stromal tumors (GIST). IM exhibits strong antiproliferative effects but fails to induce sufficient levels of apoptosis resulting in low pathologic ...
Bauer, Sebastian +11 more
core +4 more sources
Communications BiologyEnergy homeostasis and sleep have a bidirectional relationship. Cereblon (CRBN) regulates energy levels by ubiquitinating the AMP-activated protein kinase(AMPK), an energy sensor. However, whether CRBN participates in sleep is unclear.
Jun-Hyung Jung +10 more
doaj +1 more source
WorldThis research presents a synthesis of social entrepreneurship (SE) in rural communities with a tourism vocation, adopting a systemic perspective applied to the case of Yecapixtla, Morelos, Mexico.
Ricardo Tejeida-Padilla +4 more
doaj +1 more source
A Surprise Visitor at Cesarean Section: Gastrointestinal Stromal Tumor of the Uterus
Middle East Journal of Cancer, 2020 Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that almost always arise from the GI tract and account for 0.1-3% of GI tumors. During pregnancy, GIST is highly unusual given the predilection of this tumor to appear in the fifth to ...
Simon Raif Marcos +5 more
doaj +1 more source