Results 31 to 40 of about 725 (179)
The role of renal transporters and novel regulatory interactions in the TAL that control blood pressure [PDF]
, 2017 Hypertension (HTN), a major public health issue is currently the leading factor in the global burden of disease, where associated complications account for 9.4 million deaths worldwide every year (98).
Dominiczak, Anna +2 more
core +1 more source
Erythrocytosis in a Patient with Type 1 Diabetes Mellitus and Concomitant Gitelman’s Syndrome
Endocrinology Research and Practice, 2016 Gitelman’s syndrome (GS) is characterized by hypokalemia, hypomagnesaemia, hypocalciuria, metabolic alkalosis, and neurological symptoms. The association of GS with type 1 diabetes is rare, described only in a few case reports.
Müge Keskin +6 more
doaj +1 more source
Journal of Medicine, 1970 Gitleman syndrome is a rare entity. It is a benign disorder that can present with many metabolic derangements. Here we report a patient presenting with recurrent episodes of muscle weakness, muscle cramps that was diagnosed as a cas of Gitlemans syndrome.
Minhaj Rahim Choudhury +2 more
openaire +2 more sources
Gitelman syndrome and pregnancy [PDF]
Clinical Kidney Journal, 2012 Gitelman syndrome (GS) is an autosomal-recessive condition characterized by hypokalemia, hypomagnesemia and hypocalciuria. Very little information is available in the literature to guide the management of pregnant patients with GS. We report a case of a 27-year-old woman with GS who became pregnant and despite persistent hypokalemia and hypomagnesemia ...
Moustakakis, Michael N. +1 more
openaire +2 more sources
Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]
, 2018 The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
core +1 more source
Chondrocalcinosis and Gitelman syndrome [PDF]
QJM, 2016 A 37-year-old Polish lady presented left knee pain causing reduced mobility and time off work. She also complained of intermittent episodes of fatigue. Knee X-ray showed marked chondrocalcinosis (Figure 1). Serum electrolytes revealed a potassium level of 2.8 mmol/l and magnesium of 0.46 mmol/l and a hypochloraemic metabolic alkalosis.
Z, Iqbal, J A, Sayer
openaire +2 more sources
Indian Journal of Human Genetics, 2006 Classic Bartter’s syndrome is primary renal tubular hypokalemic metabolic alkalosis with normocalciuria or hypercalciuria, a severe disorder and Gitelman’s syndrome is primary renal tubular hypokalemic metabolic alkalosis with hypocalciuria and magnesium deficiency, a benign disorder.
NithyanandaK Chowta, MuktaN Chowta
+4 more sources
Gitelman's syndrome - incidentally detected in an elderly female [PDF]
, 2016 Potassium is critical for many important cell functions. Hereditary tubulopathies can also present in adults with symptoms of recurrent hypokalemia. A 60 year female who was worked up for persistent hypokalemia during repeated admission with different ...
R., Rahul, Sharma, Raghava
core +2 more sources
Thiazides induce glucose intolerance through inhibition of mitochondrial carbonic anhydrase 5b in β-cells [PDF]
, 2022 Thiazides are associated with glucose intolerance and new onset diabetes mellitus, but the molecular mechanisms remain elusive. The aim of this study was to decipher the molecular basis of thiazide-induced glucose intolerance.
Albano, Giuseppe +5 more
core +1 more source
Gitelman syndrome associated with chondrocalcinosis: description of two cases [PDF]
, 2011 Gitelman syndrome is a rare inherited tubulopathy, characterized by hypomagnesemia, hypokalemia, metabolic alkalosis, hypocalciuria and hyperreninemic hyperaldosteronism.
C. Bertolazzi +7 more
core +2 more sources