Results 41 to 50 of about 762 (149)

Acceptable standards for clinic‐based digital cognitive assessments: Recommendations from the Global CEO Initiative on Alzheimer's Disease

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract The rising prevalence of mild cognitive impairment (MCI) and dementia, combined with persistent underdiagnosis, is driving an increased need for scalable cognitive assessment tools. Digital cognitive assessments (DCAs) offer a promising solution by addressing longstanding barriers to routine cognitive testing and diagnosis. However, variations
Louisa I. Thompson, Barak Gaster, Dustin B. Hammers, Sol Fittipaldi, A. M. Barrett, Katherine A. Partrick, Emily Scholler, Benjamin Tiede, Christopher R. Butler, the CEOi Digital Cognitive Assessment Workgroup   +9 more
wiley   +1 more source

Cardiac arrhythmias and rhabdomyolysis in Bartter-Gitelman patients [PDF]

, 2018
Recent data demonstrate that patients affected with hypokalemic salt-losing tubulopathies are prone to acute cardiac arrhythmias and rhabdomyolysis. The tendency to these potentially fatal complications is especially high if chronic hypokalemia is severe,
Bettinelli, Alberto, Bianchetti, Mario, Caiata-Zufferey, Maria, Cortesi, Cinzia, Giannini, Olivier, Lava, Sebastiano, Tammaro, Fabiana   +6 more
core  

Extracellular vesicles: structure, function, and potential clinical uses in renal diseases [PDF]

, 2013
Interest in the role of extracellular vesicles in various diseases including cancer has been increasing. Extracellular vesicles include microvesicles, exosomes, apoptotic bodies, and argosomes, and are classified by size, content, synthesis, and function.
Borges, Fernanda Teixeira, Reis, L. A., Schor, Nestor   +2 more
core   +2 more sources

Recurrent Nephrolithiasis and Beyond: The Long Diagnostic Odyssey of a Case of CLDN16 Mutation

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis (FHHNC) is a rare tubulopathy resulting from mutations in the CLDN16 and CLDN19 genes. The affected individuals commonly present with polyuria, polydipsia, excessive urinary magnesium (Mg) and calcium (Ca) wasting, nephrocalcinosis, nephrolithiasis, recurrent urinary tract ...
Abdullah Al Noman Bhuiyan, Nazia Akter, Tahniyah Haq, Md. Fariduddin, Shahjada Selim   +4 more
wiley   +1 more source

Renal involvement in psychological eating disorders [PDF]

, 2011
Psychological eating disorders--anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder--are an increasing public health problem with severe clinical manifestations: hypothermia, hypotension, electrolyte imbalance, endocrine disorders and ...
Li Cavoli, G, MULE', Giuseppe, Rotolo, U.   +2 more
core   +1 more source

Familial Hypomagnesemia With Hypercalciuria and Nephrocalcinosis in a 7‐Year‐Old Girl: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare autosomal recessive renal tubular disorder, caused by mutations in the Claudin‐16 or Claudin‐19 genes. It is characterized by renal wasting of calcium and magnesium, bilateral nephrocalcinosis, and progression to kidney failure eventually.
Rummana Tazia Tonny, Farhana Akter Mumu, Shanjida Sharmim, Syed Saimul Huque   +3 more
wiley   +1 more source

Gitelman’s syndrome presented with tetany: a case report

IMC Journal of Medical Science, 2012
Gitelman’s syndrome is an autosomal recessive disorder caused by a defect of the thiazide-sensitive sodium chloride co-transporter at the distal tubule, characterized by hypomagnesemia, hypokalemic alkalosis and hypocalciuria. We report a case of Gitlman’
Md. Zahid Alam, AMB Safdar, Shabnam Jahan Hoque, Rownak Jahan Tamanna, Rowsan Ara, MM Zahurul Alam Khan   +5 more
doaj  

The miRNA Expression of Urinary Extracellular Vesicles in Patients With Gitelman Syndrome: The Role of hsa‐let‐7d‐3p

The FASEB Journal, Volume 39, Issue 21, 15 November 2025.
This study identifies differentially expressed miRNAs in urinary extracellular vesicles and kidney biopsies from Gitelman syndrome patients. In particular, hsa‐let‐7d‐3p is the only upregulated miRNA that negatively regulates NEDD4L, a key modulator of sodium transport.
Chao‐Ting Chen, Shih‐Hua Lin, Min‐Hsiu Chen, Hsin‐Yi Chang, Min‐Hua Tseng, Yii‐Jwu Lo, Kuan‐Chieh Peng, Che‐Chung Huang, Chih‐Chien Sung   +8 more
wiley   +1 more source

Aldosterone modulates the association between NCC and ENAC [PDF]

, 2017
Distal sodium transport is a final step in the regulation of blood pressure. As such, understanding how the two main sodium transport proteins, the thiazide-sensitive sodium chloride cotransporter (NCC) and the epithelial sodium channel (ENaC), are ...
Al-Khalili, Otor, Eaton, Douglas C., Hoover, Robert S., Mallick, Rickta, Mistry, Abinash C., Theilig, Franziska, Wynne, Brandi M.   +6 more
core   +1 more source

Neural Signatures of Flattened Emotional Experience in Patients With Early Multiple Sclerosis: A Bayesian Approach

Brain and Behavior, Volume 15, Issue 11, November 2025.
This fMRI‐study investigated emotional processing in patients with early MS and in healthy controls. We found flattened emotional experience associated with increased functional connectivity and brain response in the DLPFC and amygdala in patients. This suggests a disease‐related adaptive upregulation of the emotion processing and regulation network in
Torsten Wüstenberg, René Gieß, Judith Bellmann‐Strobl, Hagen Kunte, Friedemann Paul, Thomas D. Hälbig   +5 more
wiley   +1 more source