Results 121 to 130 of about 3,305,571 (308)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 1967 de Give Michel. Joaquín Carreras Artau et Juan Tusquets Terrats, Apports hispaniques à la philosophie chrétienne de l'Occident. In: Revue Philosophique de Louvain. Troisième série, tome 65, n°85, 1967. pp.
de Give, Michel
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Boy's & girl's illustrated olio.
Prefatory note signed: D.W.Includes the poem "Give!
Sigourney, L. H. (Lydia Howard), 1791-1865 Give! give!
core
Carlo Boyer, Sant' Agostino filosofo
, 1966 de Give Michel. Carlo Boyer, Sant' Agostino filosofo. In: Revue Philosophique de Louvain. Troisième série, tome 64, n°82, 1966. pp.
de Give, Michel
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 1966 de Give Michel. Ps.-Plutarco, De fato (Περὶ εἱμαρμένης). Introduzione, testo, commento, traduzione di Ernesto Valgiglio. In: Revue Philosophique de Louvain. Troisième série, tome 64, n°84, 1966. pp.
de Give, Michel
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source