Results 241 to 250 of about 3,305,571 (308)

Existence of Finite Time Blow-Up in Keller-Segel System. [PDF]

Ann PDE
Buseghin F, Dávila J, Del Pino M, Musso M.   +3 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Divergent synthesis of indenoisoquinolines and indenoisochromenes by rhodium-catalysed cyclocondensation of <i>N</i>-substituted benzamides with 2-diazoindenediones. [PDF]

RSC Adv
Kim DY, Kimura Y, Miura R, Kondo T.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Structure-Based Drug Discovery of Triazine Derivatives as Potent and Orally Bioavailable AXL Inhibitors for Cancer Therapy. [PDF]

ACS Omega
Sun M, Wu S, Zhong Y, Xi N, Cao Q.
europepmc   +1 more source

A decade of dedication: Giving, giving, giving... and giving up teaching

, 2012
Mulholland, Judith, Wallace, John
openaire   +1 more source

Prosociality predicts connectedness with nature and soil. [PDF]

Front Psychol
Neaman A, Palomo-Vélez G, Castro M, Schultz PW.   +3 more
europepmc   +1 more source

Sociodemographic Disparities in Atopic Dermatitis Prevalence in Spain. [PDF]

J Clin Med
Cayuela L, Bueno-Molina RC, Hernández-Rodríguez JC, Sendín-Martín M, Pereyra-Rodríguez JJ, Cayuela A.   +5 more
europepmc   +1 more source

Total Synthesis of Kayeassamin A and Mammeasin A: Overcoming Challenges in the Construction of Sterically Overcrowded Pentasubstituted Coumarin Frameworks. [PDF]

J Org Chem
Takashima K, Nishikawa H, Hasuda S, Kurihara K, Terada M, Maekawa R, Marumoto S, Ishikawa F, Morikawa T, Tanabe G.   +9 more
europepmc   +1 more source

A Stepwise, Nitrosonium-Catalyzed Aerobic Oxidation of Thiols to Disulfides and Thiosulfonates. [PDF]

J Org Chem
Shankar M, Hou DR.
europepmc   +1 more source