Results 121 to 130 of about 220,015 (302)

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

A simple conceptual model of abrupt glacial climate events [PDF]

open access: yes, 2007
Here we use a very simple conceptual model in an attempt to reduce essential parts of the complex nonlinearity of abrupt glacial climate changes (the so-called Dansgaard-Oeschger events) to a few simple principles, namely (i) a threshold process, (ii) an
Braun, H.   +3 more
core   +4 more sources

Glacial Isostatic Uplift in the Tibetan Plateau and Surroundings

open access: yesGeophysical Research Letters
The Tibetan Plateau and surroundings host the largest number of modern glaciers outside the polar regions. However, the impact of (de)glaciation on present‐day geodetic measurements remains unclear.
Shaozhuo Liu, Sigurjón Jónsson
doaj   +1 more source

A deep Tasman outflow of Pacific waters during the last glacial period. [PDF]

open access: yesNat Commun, 2022
Struve T   +4 more
europepmc   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles   +14 more
wiley   +1 more source

Evolutionary and demographic correlates of Pleistocene coastline changes in the Sicilian wall lizard Podarcis wagleriana [PDF]

open access: yes, 2019
Aim Emergence of coastal lowlands during Pleistocene ice ages might have provided conditions for glacial expansions (demographic and spatial), rather than contraction, of coastal populations of temperate species. Here, we tested these predictions in the
Canestrelli, Daniele   +6 more
core   +1 more source

Consequences of the Last Glacial Period on the Genetic Diversity of Southeast Asians. [PDF]

open access: yesGenes (Basel), 2022
Branco C   +3 more
europepmc   +1 more source

The Physician‐Scientist Pipeline for Pediatric Rheumatology – Current Landscape and Future Perspectives.

open access: yesArthritis Care &Research, Accepted Article.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu   +2 more
wiley   +1 more source

Tri-dimensional Model of the Radovna Glacier from the Last Glacial Period

open access: yesGeologija, 2016
The Radovna River Valley is located in the northwest of Slovenia, in the Julian Alps, and bounded by two plateaus – Pokljuka in the south and Mežakla in the north.
Luka Serianz
doaj   +1 more source

Real‐world trends in prenatal antirheumatic drug utilization in Ontario, Canada: A cross‐sectional time‐series analysis

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

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