Results 31 to 40 of about 38,745 (258)

A tropical speleothem record of glacial inception, the South American Summer Monsoon from 125 to 115 ka [PDF]

open access: yesClimate of the Past, 2015
Relatively few marine or terrestrial paleoclimate studies have focused on glacial inception, the transition from an interglacial to a glacial climate state.
S. J. Burns   +3 more
doaj   +1 more source

The Glacial Period [PDF]

open access: yesNature, 1881
PLEASE correct an error in the notice of my paper on the Glacial Period (NATURE, vol. xxiv. p. 364). It is on the western slope of New Zealand that the glaciers reach to the highest mean annual temperature (10° C., or 50° F.) as well as to the lowest level.
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Vegetation of central Carpathians foreland at the Late Glacial period

open access: yesБіологічні студії, 2009
Palaeopalynological analysis of two organic Quaternary deposits revealed that plant community of taiga-type with sizeable xerotic herbaceous coenosis were spread in the central part of Carpathian Foreland during the Late Glacial period. The forest-steppe
N. Kalinovych
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Animal remains from the post-glacial warm period in Norway

open access: yesFauna Norvegica, 1989
Bone material excavated in 1954 at a cave on the island of Sandsøya, Sunnmøre, W. Norway is described. The material consists of c. 70 000 bones, including 124 species of birds, and has been dated to c. 6600 to 3600 years B. P.
Rolf W. Lie
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Former Glacial Periods [PDF]

open access: yesNature, 1890
I HAVE long felt convinced that geologists are being misled in reference to former glacial epochs by failing to give due thought to a consideration referred to on former occasions,1 viz. that when the present surface of the globe has been disintegrated, washed into the sea, and transformed into rock, there will undoubtedly then be about as little ...
openaire   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Desertification and Related Climate Change in the Alashan Plateau since the Last 40 ka of the Last Glacial Period

open access: yesAtmosphere, 2023
Clues of climate change on the Alashan Plateau since the last glacial period (40 ka) are important for revealing the mechanism of desertification of middle-latitude deserts in the Northern Hemisphere (NH).
Bingqi Zhu, Limin Yang
doaj   +1 more source

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