Results 51 to 60 of about 220,015 (302)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Vegetation of central Carpathians foreland at the Late Glacial period
Біологічні студії, 2009 Palaeopalynological analysis of two organic Quaternary deposits revealed that plant community of taiga-type with sizeable xerotic herbaceous coenosis were spread in the central part of Carpathian Foreland during the Late Glacial period. The forest-steppe
N. Kalinovych
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Evolution of the Great Tehuelche Paleolake in the Torres del Paine National Park of Chilean Patagonia during the Last Glacial Maximum and Holocene [PDF]
, 2012 Indexación: Web of Science; ScieloRESUMEN. Una serie de morrenas glaciares se distribuyen desde el margen oriental de la cuenca de drenaje Torres del Paine a cerca del actual margen de los Campos de Hielo Patagónico, junto con una serie de terrazas ...
Airo, Alessandro +4 more
core +2 more sources
Animal remains from the post-glacial warm period in Norway
Fauna Norvegica, 1989 Bone material excavated in 1954 at a cave on the island of Sandsøya, Sunnmøre, W. Norway is described. The material consists of c. 70 000 bones, including 124 species of birds, and has been dated to c. 6600 to 3600 years B. P.
Rolf W. Lie
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Reduced plant water status under sub-ambient pCO2 limits plant productivity in the wild progenitors of C3 and C4 cereals. [PDF]
, 2016 BACKGROUND AND AIMS: The reduction of plant productivity by low atmospheric CO2 partial pressure (pCO2) during the last glacial period is proposed as a limiting factor for the establishment of agriculture.
Colin P. Osborne +5 more
core +1 more source
Atmosphere, 2023 Clues of climate change on the Alashan Plateau since the last glacial period (40 ka) are important for revealing the mechanism of desertification of middle-latitude deserts in the Northern Hemisphere (NH).
Bingqi Zhu, Limin Yang
doaj +1 more source
Nature, 1890 I HAVE long felt convinced that geologists are being misled in reference to former glacial epochs by failing to give due thought to a consideration referred to on former occasions,1 viz. that when the present surface of the globe has been disintegrated, washed into the sea, and transformed into rock, there will undoubtedly then be about as little ...
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source