Results 71 to 80 of about 220,015 (302)

Landscape genetics reveal broad and fine‐scale population structure due to landscape features and climate history in the northern leopard frog (Rana pipiens) in North Dakota [PDF]

open access: yes, 2018
Prehistoric climate and landscape features play large roles structuring wildlife populations. The amphibians of the northern Great Plains of North America present an opportunity to investigate how these factors affect colonization, migration, and current
Fisher, Justin D.L.   +4 more
core   +1 more source

Sea surface temperature changes in the southern California borderlands during the last glacial-interglacial cycle [PDF]

open access: yes, 1996
A variety of evidence suggests that average sea surface temperatures (SSTs) during the last glacial maximum in the California Borderlands region were significantly colder than during the Holocene.
Bandy   +52 more
core   +2 more sources

Controls on Alpine Lake Dynamics, Tien Shan, Central Asia

open access: yesRemote Sensing, 2022
The number and area of alpine lakes in Tien Shan (TS) are rapidly growing in response to a warming climate and retreating glaciers. This paper presents a comparative analysis of lake classification and changes by dividing alpine lakes (within a 10 km ...
Qifei Zhang   +5 more
doaj   +1 more source

Periodicity of Glacial Epochs [PDF]

open access: yesNature, 1886
PERMIT me to ask, as a matter of international comity in science, the help of my learned British colleagues in the following matter.
openaire   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Middle Archaic Complex of Northwest Arkansas [PDF]

open access: yes, 1969
After the end of the Wisconsin glacial there occurred an interval called the Neothermal in the southwestern portion of the United States. The Neothermal is comprised of three consecutive tempera-ture intervals: the Anathermal, Altithermal, and ...
Beckman, Michael A.
core   +2 more sources

Contribution à l'évaluation de la vitesse d'érosion des cirques glaciaires de quelques massifs anciens européens

open access: yesPhysio-Géo, 2011
Morphometric data from a sample of thirty glacial cirques located in European basement regions (Black Forest, South-West Ireland and Wales) assess the rate of glacial erosion.
Francis Huguet
doaj   +1 more source

The De Long Trough: a newly discovered glacial trough on the East Siberian continental margin [PDF]

open access: yesClimate of the Past, 2017
Ice sheets extending over parts of the East Siberian continental shelf have been proposed for the last glacial period and during the larger Pleistocene glaciations.
M. O'Regan   +23 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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