Results 181 to 190 of about 28,257 (311)

Talin1 Adhesion Morphology and Colocalization With Tensin3 Are Largely Unaffected by Polyacrylamide Substrate Stiffness

Cytoskeleton, EarlyView.
ABSTRACT Cells sense the stiffness of their extracellular matrix (ECM) and adapt their behavior accordingly. We investigated how ECM stiffness affects the spatial organization of talin1, a key mechanosensitive focal adhesion protein. Using polyacrylamide (PA) hydrogels with tunable stiffnesses (0.2–188 kPa), we analyzed cell morphology, migration ...
Joanna Hajduk, Patrycja Twardawa, Sylwia Bobis‐Wozowicz, Marta Szewczyk, Zenon Rajfur, Zbigniew Baster   +5 more
wiley   +1 more source

Redox Dynamics of the Atmosphere and Oceans Induced by the Paleoproterozoic Snowball Earth Events. [PDF]

Geobiology
Harada M, Miura Y, Watanabe Y, Ozaki K.
europepmc   +1 more source

Fixation Induces Mislocalization of Thin Filament Components in Caenorhabditis elegans Striated Muscle

Cytoskeleton, EarlyView.
ABSTRACT The simple nematode Caenorhabditis elegans has long served as a powerful genetic model system for studying muscle structure and function, with sarcomeres of the striated body wall muscle (BWM) that are considered largely homologous to those in vertebrates.
Michael J. Kimmich, Pu Zhang, Bob Goldstein, David Pruyne   +3 more
wiley   +1 more source

Reduced N₂ fixation in the tropical Atlantic Ocean during the warm late Pliocene. [PDF]

Nat Commun
Yehudai M, Farmer JR, Straub M, Studer AS, Oesch L, Creel RC, Schiebel R, Auderset A, Lawrence K, Ogretmen N, Haug GH, Sigman DM, Martínez-García A.   +12 more
europepmc   +1 more source

An Investigation Into the Yields of 3,4‐Methylenedioxyphenyl‐2‐propanone (MDP2P) From Glycidate Pre‐Precursors

Drug Testing and Analysis, EarlyView.
Hydrolysis of the glycidate pre‐precursors MMDMG and EMDMG was evaluated for MDP2P production. Acid hydrolysis of MMDMG (HCl, 100°C, 18 h) yielded the highest MDP2P recovery (79%), whereas base hydrolysis produced only slightly lower yields (73%), demonstrating both pathways are effective routes to this key MDMA precursor.
Alexandra L. Mercieca, Ella S. Schuett, Andrew M. McDonagh, Shanlin Fu, Morgan Alonzo   +4 more
wiley   +1 more source

Major sea level fall during the Pliocene M2 glaciation. [PDF]

Nat Commun
Yang Z, Lear CH, Barker S, Elsey J, Gasson E, Rosenthal Y, Slater SM, Thomas-Sparkes A.   +7 more
europepmc   +1 more source

Spatio‐temporal dynamics of ringed seal density and habitat use in the Arctic's Last Ice Area

Ecography, EarlyView.
The Arctic is warming at approximately four times the global rate, driving widespread decline in sea ice extent, thickness, and seasonal duration. The ecological consequences of these rapid changes remain poorly understood within the Last Ice Area, a region that includes northern Ellesmere Island and the northwest of Greenland, projected to retain ...
Roxanne D. MacLean, Gregory W. Thiemann, Steven H. Ferguson, Katie R.N. Florko, Cody G. Carlyle, Kelsey F. Johnson, Lisa C. Matthes, Christine Michel, Brent G. Young, David J. Yurkowksi   +9 more
wiley   +1 more source

Tectonism rather than "snowball Earth" glaciation is responsible for the Great Unconformity. [PDF]

Proc Natl Acad Sci U S A
Zhan RR, Duan L, Zattin M, Christie-Blick N, Wan B, Wei RH, Yang Z, Wang J, Gou L, Olivetti V, Chen KY, Zhang X.   +11 more
europepmc   +1 more source

Spatially heterogenous range dynamics since the Last Glacial Maximum underpin the modern bimodal latitudinal diversity gradient in planktonic foraminifera

Ecography, EarlyView.
The modern latitudinal diversity gradient (LDG) of planktonic foraminifera is bimodal, with a distinct depression near the equator surrounded by mid‐latitude diversity peaks. This pattern emerged after the Last Glacial Maximum (LGM; 19–23 ka), but it remains unclear how species' spatial dynamics contributed to its formation.
Tasnuva Ming Khan, Marina C. Rillo, Lukas Jonkers, Isaiah E. Smith, Ádám T. Kocsis, Wolfgang Kiessling   +5 more
wiley   +1 more source

Regime shift to extensive valley glaciations over High Mountain Asia during the Early-Middle Pleistocene. [PDF]

Nat Commun
Yan Q, Owen LA, Wei T, Hughes PD, Kong X, Jiang N, Zhang J, Zhang Z, Wang H.   +8 more
europepmc   +1 more source