Results 81 to 90 of about 204,044 (338)

Including debris cover effects in a distributed model of glacier ablation [PDF]

open access: yes, 2012
Distributed glacier melt models generally assume that the glacier surface consists of bare exposed ice and snow. In reality, many glaciers are wholly or partially covered in layers of debris that tend to suppress ablation rates.
Andersen   +48 more
core   +1 more source

A Time‐Programmed Bilayer Wound Dressing for Dynamic Microenvironment Modulation and Full‐Thickness Regeneration in Diabetic Wounds

open access: yesAdvanced Science, EarlyView.
The Polyphenol+PDGF‐BB scaffold fabrication (Panel A) and its dual wound healing effects (Panel B: anti‐inflammation and accelerated tissue remodeling). ABSTRACT Chronic diabetic wounds suffer from dysfunctional repair programs due to accumulated advanced glycation end products (AGEs) and persistent inflammation in hyperglycemic microenvironments ...
Lei Yi   +7 more
wiley   +1 more source

First ground penetrating radar survey on Monte Perdido glacier (Pyrenees) [PDF]

open access: yes, 2016
Producción CientíficaThe project “The Monte Perdido Glacier: Monitoring the glacial dynamic and the associated cryospheric processes as indicators of global change” (National Park´s 2013 Fund) aims to study the recent dynamic and degradation of this ice
Heras Barrueco, Andrés   +5 more
core   +1 more source

Suitability of ground-based SfM-MVS for monitoring glacial and periglacial processes [PDF]

open access: yes, 2016
Photo-based surface reconstruction is rapidly emerging as an alternative survey technique to lidar (light detection and ranging) in many fields of geoscience fostered by the recent development of computer vision algorithms such as structure from motion ...
Carturan, Luca   +6 more
core   +2 more sources

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

The spatial variation of Asian dust and marine aerosol contributions to glaciochemical signals in central Asia [PDF]

open access: yes, 1992
Short-term (6 months to 17 years) glaciochemical records have been collected from several glacier basins in the mountains of central Asia. The spatial distribution of snow chemistry in central Asia is controlled by the influx of dust from the large ...
Mayewski, Paul A, Wake, Cameron P
core   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

Evaluation of existing and new methods of tracking glacier terminus change [PDF]

open access: yes, 2014
ACKNOWLEDGEMENTS The authors thank two anonymous reviewers for constructive comments that helped to improve the manuscript. This research was financially supported by J.M.L.’s PhD funding from UK Natural Environment Research Council grant No.
Brice R. Rea   +4 more
core   +2 more sources

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning   +18 more
wiley   +1 more source

Pared-down landscapes in Antarctica [PDF]

open access: yes, 1971
The frigid-arid climate that now prevails in ice-free parts of Victoria Land, Antarctica, inhibits glacial erosion. If certain landscapes, more or less remote from the great troughs of outlet glaciers, have been glaciated in the past, as seems very ...
Cotton, C.A., Wilson, A.T.
core   +1 more source

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