Results 61 to 70 of about 582 (245)

Mass balance and area changes of glaciers in the Cordillera Real and Tres Cruces, Bolivia, between 2000 and 2016

open access: yesJournal of Glaciology, 2020
Climate change has led to a significant shrinkage of glaciers in the Tropical Andes during the last decades. Recent multi-temporal quantifications of ice mass loss at mountain range to regional scale are missing.
Thorsten Seehaus   +5 more
doaj   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang   +17 more
wiley   +1 more source

Glacier Extraction from Cloudy Satellite Images Using a Multi-Task Generative Adversarial Network Leveraging Transformer-Based Backbones

open access: yesRemote Sensing
Accurate delineation of glacier extent is crucial for monitoring glacier degradation in the context of global warming. Satellite remote sensing with high spatial and temporal resolution offers an effective approach for large-scale glacier mapping ...
Yuran Cui   +11 more
doaj   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

open access: yesAdvanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li   +8 more
wiley   +1 more source

Ice front positions for Greenland glaciers (2002–2021): a spatially extensive seasonal record and benchmark dataset for algorithm validation [PDF]

open access: yesEarth System Science Data
Glacier terminus (ice-front) positions are key indicators of glacier dynamic variability and ice–ocean–atmosphere interactions and provide essential time-varying boundary conditions for ice-sheet modelling. High-precision, spatially extensive records are
X. Lu   +9 more
doaj   +1 more source

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

open access: yesAdvanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan   +10 more
wiley   +1 more source

Glacier area shrinkage in eastern Nepal Himalaya since 1992 using high-resolution inventories from aerial photographs and ALOS satellite images

open access: yesJournal of Glaciology, 2016
To better understand the recent wide-scale changes in glacier coverage, we created and compared two glacier inventories covering eastern Nepal, based on aerial photographs (1992) and high-resolution Advanced Land Observing Satellite (ALOS) imagery (2006 ...
SUNAL OJHA   +6 more
doaj   +1 more source

Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

open access: yesAdvanced Science, EarlyView.
During renal fibrosis, SMAD3 acts as a transcription factor for CRLF1, promoting its expression and secretion. CRLF1 then binds to ITGB1 via an autocrine mechanism, activating the PI3K‐AKT signaling pathway to mediate renal fibrosis. This accelerates the progression from AKI to CKD, highlighting the therapeutic potential of targeting CRLF1 for ...
Chunjie Wang   +8 more
wiley   +1 more source

Compiling a new glacier inventory for southeastern Qinghai–Tibet Plateau from Landsat and PALSAR data

open access: yesJournal of Glaciology, 2016
Glacier change has been recognized as an important climate variable due to its sensitive response to climate change. Although there are a large number of glaciers distributed over the southeastern Qinghai–Tibetan Plateau, the region is poorly represented
LINGHONG KE   +5 more
doaj   +1 more source

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