Results 111 to 120 of about 53,515 (307)

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

Biological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson, Ellen Wohl, Laura L. Govers, Oscar Franken, Tjeerd J. Bouma, Han Olff, Britas Klemens Eriksson, Maryann S. Watson, Luísa M.S. Borges, Tjisse van der Heide   +9 more
wiley   +1 more source

The spread of non‐native species

Biological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock, Ali Serhan Tarkan, Irene Martín‐Forés, Stelios Katsanevakis, Ronaldo Sousa, Ismael Soto, Andy J. Green, Antonín Kouba, Teun Everts, Victoria Dominguez Almela, Nadège Belouard, Cang Hui, Jamie Bojko, Victor Deklerck, Margaux Boeraeve, Franz Essl, J. Robert Britton   +16 more
wiley   +1 more source

Origin and significance of 'dispersed facies' basal ice: Svínafellsjökull, Iceland [PDF]

, 2010
Dispersed facies basal ice - massive (i.e. structureless) ice with dispersed debris aggregates - is present at the margins of many glaciers and, as a product of internal glacial processes, has the potential to provide important information about the ...
Darrel A. Swift, David J. Graham, Evenson, Holdsworth, Knight, Knudsen, Lawson, Nicholas G. Midgley, Robinson, Simon J. Cook, Spedding   +10 more
core   +3 more sources

Climate scenarios of sea level rise for the northeast Atlantic Ocean: a study including the effects of ocean dynamics and gravity changes induced by ice melt

, 2008
Here we present a set of regional climate scenarios of sea level rise for the northeast Atlantic Ocean. In this study, the latest observations and results obtained with state-of-the-art climate models are combined.
Burgers, Gerrit, Drijfhout, Sybren S., Hazeleger, Wilco, Katsman, Caroline A., Oldenborgh, Geert Jan   +4 more
core   +1 more source

Geological processes shaping freshwater biodiversity: a synthesis of global evidence

Biological Reviews, EarlyView.
ABSTRACT Recent genomic data highlight the key roles of geological processes in shaping the diversification and biogeography of freshwater lineages. Specifically, physical processes such as tectonic uplift, erosion, glaciation, lake formation, and sea‐level fluctuation contribute extensively to the evolution of biotic diversity within and among ...
Jonathan M. Waters, Christopher P. Burridge, David Craw, James S. Albert   +3 more
wiley   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

Impact of ocean stratification on submarine melting of a major Greenland outlet glacier [PDF]

, 2011
Submarine melting is an important balance term for tidewater glaciers1,2 and recent observations point to a change in the submarine melt rate as a potential trigger for the widespread acceleration of outlet glaciers in Greenland3-5.
Claudia Cenedese, David Sutherland, Fiammetta Straneo, Gordon Hamilton, Kjetil Vaage, Leigh Stearns, Ruth Curry   +6 more
core   +1 more source

The extension of the taxon cycle model to island plants: insights from the Canarian vascular flora

Biological Reviews, EarlyView.
ABSTRACT Taxon cycle models describe eco‐evolutionary patterns of lineage colonization, diversification, and decline across archipelagos, inferring an important role for competition amongst ecologically similar taxa in driving concurrent niche changes.
José María Fernández‐Palacios, Rüdiger Otto, Robert J. Whittaker   +2 more
wiley   +1 more source

Deriving Ice Motion Patterns in Mountainous Regions by Integrating the Intensity-Based Pixel-Tracking and Phase-Based D-InSAR and MAI Approaches: A Case Study of the Chongce Glacier

Remote Sensing, 2016
As a sensitive indicator of climate change, mountain glacier dynamics are of great concern, but the ice motion pattern of an entire glacier surface cannot be accurately and efficiently generated by the use of only phase-based or intensity-based methods ...
Shiyong Yan, Zhixing Ruan, Guang Liu, Kazhong Deng, Mingyang Lv, Zbigniew Perski   +5 more
doaj   +1 more source