Results 61 to 70 of about 378,079 (290)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

Simulating seasonal evolution of subglacial hydrology at a surging glacier in the Karakoram

Journal of Glaciology
Glacier motion, retreat and glacier hazards such as surges and glacial lake outburst floods (GLOFs) are likely underpinned by subglacial hydrology. Recent advances in subglacial hydrological modeling allow us to shed light on subglacial processes that ...
Neosha G. Narayanan, Aleah N. Sommers, Winnie Chu, Jakob F. Steiner, Muhammad Adnan Siddique, Colin R. Meyer, Brent Minchew   +6 more
doaj   +1 more source

Modeling 2m air temperatures over mountain glaciers: Exploring the influence of katabatic cooling and external warming [PDF]

, 2015
Air temperature is one of the most relevant input variables for snow and ice melt calculations. However, local meteorological conditions, complex topography, and logistical concerns in glacierized regions make the measuring and modeling of air ...
J. M. Shea, F. Pellicciotti, Ayala, Alvaro, A. Ayala, Shea, J. M., Pellicciotti, Francesca, Pellicciotti, F., Ayala, A.   +7 more
core   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Terminus advance, kinematics and mass redistribution during eight surges of Donjek Glacier, St. Elias Range, Canada, 1935 to 2016

Journal of Glaciology, 2019
Donjek Glacier has an unusually short and regular surge cycle, with eight surges identified since 1935 from aerial photographs and satellite imagery with a ~12 year repeat interval and ~2 year active phase.
WILLIAM KOCHTITZKY, HESTER JISKOOT, LUKE COPLAND, ELLYN ENDERLIN, ROBERT MCNABB, KARL KREUTZ, BRITTANY MAIN   +6 more
doaj   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Glacier Surface Heatwaves Over the Tibetan Plateau

Geophysical Research Letters, 2023
The Tibetan Plateau (TP) has warmed at a rate twice the global average and presents unique warming patterns in surface temperature changes. However, key characteristics of glacier surface heatwave duration and intensity over the TP during the present ...
Wenfeng Chen, Tandong Yao, Guoqing Zhang, R. Iestyn Woolway, Wei Yang, Fenglin Xu, Tao Zhou   +6 more
doaj   +1 more source

The distribution of basal motion beneath a High Arctic polythermal glacier [PDF]

, 2003
The longitudinal pattern of surface velocity of a large, predominantly colds polythermal glacier (John Evans Glacier, Ellesmere Island, Canada) was measured over summer and winter periods.
Nienow, Peter W., Copland, L, Nienow, P, Bingham, RG, Sharp, M.J., Bingham, Robert George, Copland, L., Copland, Luke, Bingham, R.G., Sharp, Martin J., Sharp, MJ, Nienow, P., Bingham, Robert G.   +12 more
core   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source