Results 101 to 110 of about 161,944 (383)

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

open access: yesAdvanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu   +16 more
wiley   +1 more source

Disaggregating geodetic glacier mass balance to annual scale using remote-sensing proxies

open access: yesJournal of Glaciology, 2023
Decadal-scale, high-resolution geodetic measurements of glacier thinning have transformed our understanding of glacier response to climate change. Annual glacier mass balance can be estimated using remote-sensing proxies like snow-line altitude.
Argha Banerjee   +2 more
doaj   +1 more source

Representing moisture fluxes and phase changes in glacier debris cover using a reservoir approach [PDF]

open access: yes, 2014
Due to the complexity of treating moisture in supraglacial debris, surface energy balance models to date have neglected moisture infiltration and phase changes in the debris layer.
Brock, Benjamin   +5 more
core   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

open access: yesAdvanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang   +12 more
wiley   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

open access: yesAdvanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao   +5 more
wiley   +1 more source

Mass balance evolution of Martial Este Glacier, Tierra del Fuego (Argentina) for the period 1960–2099 [PDF]

open access: yes, 2009
The Martial Este Glacier in southern Tierra del Fuego was studied in order to estimate the surface mass balance from 1960 until 2099. For this reason a degree-day model was calibrated.
C. Schneider   +3 more
core   +1 more source

Glaciers in Svalbard: mass balance, runoff and freshwater flux [PDF]

open access: yesPolar Research, 2003
Gain or loss of the freshwater stored in Svalbard glaciers has both global implications for sea level and, on a more local scale, impacts upon the hydrology of rivers and the freshwater flux to fjords. This paper gives an overview of the potential runoff from the Svalbard glaciers. The freshwater flux from basins of different scales is quantified.
Hagen, Jon Ove   +3 more
openaire   +3 more sources

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

open access: yesAdvanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos   +12 more
wiley   +1 more source

The Mass balance modelling of Spitzbergen glaciers [PDF]

open access: yesPolar Research, 2018
This thesis deals with a series of mass balance studies carried out on two glaciers in north-west Spitsbergen, Midre Lovenbreen and Austre Broggerbreen, using an energy balance model. A general description of glaciers, including their classification and the manner in which their surfaces may be sub-divided, is carried out.
openaire   +3 more sources

Favorable climatic regime for maintaining the present-day geometry of the Gregoriev Glacier, Inner Tien Shan [PDF]

open access: yesThe Cryosphere, 2011
We conducted 2 yr (2005–2007) of in situ meteorological and glaciological observations on the Gregoriev Glacier, a flat-top glacier within the Inner Tien Shan, Kyrgyzstan. Relative carrier-phase GPS surveys reveal a vertical lowering at the summit of the
K. Fujita   +6 more
doaj   +1 more source

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