Results 1 to 10 of about 696,439 (160)

Reconciling Svalbard Glacier Mass Balance

Frontiers in Earth Science, 2020
Since the first estimates of Svalbard-wide glacier mass balance were made in the early 2000s, there has been great progress in remote sensing and modeling of mass balance, existing field records have been extended, field records at new locations have ...
Thomas V. Schuler, Thomas V. Schuler, Jack Kohler, Nelly Elagina, Jon Ove M. Hagen, Andrew J. Hodson, Andrew J. Hodson, Jacek A. Jania, Andreas M. Kääb, Bartłomiej Luks, Jakub Małecki, Geir Moholdt, Veijo A. Pohjola, Ireneusz Sobota, Ward J. J. Van Pelt   +14 more
doaj   +3 more sources

Mass Balance and Metabolism of 14C‐Atogepant in Healthy Male Participants: Findings of a Phase 1 Clinical Trial [PDF]

Clinical and Translational Science
Atogepant, a calcitonin gene‐related peptide (CGRP) receptor antagonist, is approved for the preventive treatment of migraine in adults. This open‐label, phase 1 study examined radiolabeled atogepant (14C‐atogepant) metabolism, elimination, and mass ...
Ramesh R. Boinpally, Pushpa Chandrasekar, Joshua M. Rowe   +2 more
doaj   +2 more sources

Development of Certified Reference Material of L-Thyroxine by Using Mass Balance and Quantitative Nuclear Magnetic Resonance [PDF]

Molecules
L-thyroxine (T4) is an important hormone for diagnosing and evaluating thyroid function disorders. As outlined in ISO17511, having a certified reference material (CRM) is crucial for ensuring that the results of clinical tests are traceable to the SI ...
Qiang Zhao, Weifei Zhang, Dan Song, Xirui Zhou, Xianjiang Li, Huan Yao, Wenjing Xing, Hongmei Li, Jian Ma, Peng Xiao   +9 more
doaj   +2 more sources

Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation

Frontiers in Endocrinology, 2022
Peripheral nerves allow a bidirectional communication between brain and adipose tissues, and many studies have clearly demonstrated that a loss of the adipose nerve supply results in tissue dysfunction and metabolic dysregulation.
Magdalena Blaszkiewicz, Gilian Gunsch, Jake W. Willows, Miranda L. Gardner, Miranda L. Gardner, Jesse A. Sepeda, Andrew R. Sas, Kristy L. Townsend   +7 more
doaj   +1 more source

A long-term mass-balance reconstruction (1974–2021) and a decadal in situ mass-balance record (2011–2021) of Rikha Samba Glacier, central Himalaya

Journal of Glaciology, 2023
Despite their importance for regional water resource planning and as indicators of climate change, records of in situ glacier mass balance remain short and spatially sparse in the Himalaya.
Tika Ram Gurung, Rijan Bhakta Kayastha, Koji Fujita, Sharad Prasad Joshi, Anna Sinisalo, James D. Kirkham   +5 more
doaj   +1 more source

Annual and seasonal glaciological mass balance of Patsio Glacier, western Himalaya (India) from 2010 to 2017

Journal of Glaciology, 2021
Improving the knowledge on Himalayan glaciers mass balance is a key to understand the present and past annual atmospheric variations and future water availability in the region.
Thupstan Angchuk, Alagappan Ramanathan, I. M. Bahuguna, Arindan Mandal, Mohd Soheb, Virendra Bahadur Singh, Somdutta Mishra, Sarvagya Vatsal   +7 more
doaj   +1 more source

Disaggregating geodetic glacier mass balance to annual scale using remote-sensing proxies

Journal of Glaciology, 2023
Decadal-scale, high-resolution geodetic measurements of glacier thinning have transformed our understanding of glacier response to climate change. Annual glacier mass balance can be estimated using remote-sensing proxies like snow-line altitude.
Argha Banerjee, Ujjwal Singh, Chintan Sheth   +2 more
doaj   +1 more source

Study of the mass balance, biotransformation and safety of [14C]SHR8554, a novel μ-opioid receptor injection, in healthy Chinese subjects

Frontiers in Pharmacology, 2023
Background: SHR8554 is a novel μ-opioid receptor-biased agonist. It has analgesic effects by selectively activating the G protein-coupled pathway. Additionally, it can weakly activate the ß-arrestin-2 pathway, resulting in a limited number of side ...
Rupeng Shi, Yi Chai, Hao Feng, Lijun Xie, Lulu Zhang, Tianqi Zhong, Juan Chen, Peng Yan, Bei Zhu, Jun Zhao, Chen Zhou   +10 more
doaj   +1 more source

Reanalysing glacier mass balance measurement series [PDF]

The Cryosphere, 2013
Glacier-wide mass balance has been measured for more than sixty years and is widely used as an indicator of climate change and to assess the glacier contribution to runoff and sea level rise.
M. Zemp, E. Thibert, M. Huss, D. Stumm, C. Rolstad Denby, C. Nuth, S. U. Nussbaumer, G. Moholdt, A. Mercer, C. Mayer, P. C. Joerg, P. Jansson, B. Hynek, A. Fischer, H. Escher-Vetter, H. Elvehøy, L. M. Andreassen   +16 more
doaj   +1 more source

Improvement of Microbial Cell Concentration Technology in the Production of Live Plague Vaccine in the Form of Orodispersible Tablets

Проблемы особо опасных инфекций, 2021
The aim of the study was to improve the procedure for the Yersinia pestis EV strain cell concentration using the system for tangential flow microfiltration with the ASF-020 filter support unit.Materials and methods. The study used the vaccine Y.
D. A. Sharov, A. A. Leshchenko, S. V. Bagin, S. V. Logvinov, D. A. Mokhov, A. V. Ezhov, A. G. Lazykin, V. V. Krupin, I. V. Kosenkov   +8 more
doaj   +1 more source