Results 141 to 150 of about 161,944 (383)

Estimation of Glacier Thickness From Surface Mass Balance and Ice Flow Velocities: A Case Study on Argentière Glacier, France

Frontiers in Earth Science, 2018
Glacier thickness distribution is a prerequisite to simulate the future of glaciers. Inaccurate thicknesses may lead to significant uncertainties in the timing of future changes to glaciers and their consequences for water resources or sea level rise ...
A. Rabatel, Olivier Sanchez, C. Vincent, D. Six   +3 more
semanticscholar   +1 more source

Potential climatic transitions with profound impact on Europe [PDF]

, 2011
We discuss potential transitions of six climatic subsystems with large-scale impact on Europe, sometimes denoted as tipping elements. These are the ice sheets on Greenland and West Antarctica, the Atlantic thermohaline circulation, Arctic sea ice, Alpine
A Born, A Ganachaud, A Ganopolski, A Hu, A Jones, A Laurian, A Levermann, A Levermann, A Levermann, A Levermann, A Schmittner, A Winguth, AA Scaife, Anders Levermann, Andrey Ganopolski, B Dickson, B Schaefli, B Zwierl, BJ Soden, BN Goswami, C Deser, C Haas, C Harris, C Schnadt, C Schoof, C Stick, C Vincent, CAPE-Last Interglaicial Project Members, CL Parkinson, D Farinotti, D Notz, D Pollard, D Stammer, DA Lashof, DA Rothrock, DB Kirk-Davidoff, DG Vaughan, Dirk Notz, DK Perovich, DM Holland, DM Lawrence, DT Shindell, DWJ Thompson, E Kriegler, E Meur Le, E Rignot, E Rignot, E Rignot, EJ Rignot, F Paul, F Paul, G Cogley, G Jouvet, G Kaser, G Manney, G Manney, G Manney, GA Meehl, GJ Oldenborgh van, H Goosse, H Hátún, HD Pritchard, HJ Schellnhuber, I Auer, I Eisenmann, I Joughin, I Joughin, I Velicogna, J Maslanik, J Noetzli, J Oerlemans, J Oerlemans, J Oerlemans, J Ridley, J Ridley, J Stroeve, J Weertman, J Yin, J Yin, J Zhang, JA Church, JC Comiso, JE Kay, JF McManus, JH Jungclaus, JL Bamber, JL Chen, JM Gregory, JM Gregory, Jonathan L. Bamber, JP Wilkinson, JR Miller, JT Overpeck, JX Mitrovica, K Eckhardt, K Zickfeld, KH Rosenlof, Kirstin Krüger, LC Sime, LH Smedsrud, M Beniston, M Dameris, M Hoelzle, M Hofmann, M Honda, M Huss, M Huss, M Huss, M Ogi, M Rex, M Rex, M Scheffer, M Stendel, M Vellinga, M Vellinga, M Wang, M Winton, M Winton, M Zemp, M Zemp, Matthias Huss, MF Meier, MM Holland, Neil R. P. Harris, NP Harris, NW Arnell, O Solomina, P Huybrechts, P Wadhams, P Wadhams, P Wadhams, Peter Wadhams, PM Forster, PU Clark, R Hock, R Lindsay, RE Kopp, RJ Braithwaite, RJ Stouffer, Ronald W. Lindsay, RP Scherer, S Amstrup, S Gruber, S Rahmstorf, S Rahmstorf, S Rahmstorf, S Rahmstorf, S Rahmstorf, S Solomon, S Solomon, S Tegtmeier, S Tietsche, SJ Evans, SJ Oltmans, SL Weber, SL Weber, SS Drijfhout, Susanne Weber, Sybren Drijfhout, T Hattermann, T Kuhlbrodt, T Naish, T Toniazzo, Timothy M. Lenton, TM Lenton, V Petoukhov, VM Kattsov, W Haeberli, W Haeberli, W Weijer, Winfried Haeberli, WJ Randel, WT Pfeffer, Y Wang, ZW Kundzewicz   +174 more
core   +1 more source

A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measures

Biotechnology Progress, EarlyView.
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu, Derek Silva, Melissa Holstein, Angela Lewandowski, Kristina Cunningham, Adam Sokolnicki, Bala Raghunath   +6 more
wiley   +1 more source

Glacier Energy and Mass Balance in the Inland Tibetan Plateau: Seasonal and Interannual Variability in Relation to Atmospheric Changes

Journal of Geophysical Research: Atmospheres, 2018
The Tibetan glaciers are greatly affected by the circulations of the westerlies and the Indian summer monsoon (ISM), but the mechanisms remain to be elucidated.
Shenghai Li, T. Yao, Wei Yang, Wusheng Yu, Meilin Zhu   +4 more
semanticscholar   +1 more source

Expanding the Toolbox for Inducible Protein Expression With Automation‐enabled Generation of Glycomimetics

Chemistry – A European Journal, EarlyView.
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. 2′‐fucosyl isopropyl‐β‐D‐thiogalactopyranose (2′F‐IPTG) and 2′‐fucosyl isobutyl‐C‐galactoside (2′F‐IBCG) mimics were explored for protein expression studies.
Ashley E. DeYong, Keevan C. Marion, Murat Ozturk, Sanjeeva Kumar Murali, Fatima Enam, Thomas J. Mansell, Nicola L. B. Pohl   +6 more
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Annual Glacier-Wide Mass Balance (2000-2016) of the Interior Tibetan Plateau Reconstructed from MODIS Albedo Products

Remote Sensing, 2018
Glaciers in the Tibetan Plateau (TP) play a crucial role in regulating agriculture irrigation, river discharge and the regional/global climate system.
Zhimin Zhang, Liming Jiang, Lin Liu, Yafei Sun, Hansheng Wang   +4 more
semanticscholar   +1 more source

Representing glaciers in a regional climate model [PDF]

, 2018
A glacier parameterization scheme has been developed and implemented into the regional climate model REMO. The new scheme interactively simulates the mass balance as well as changes of the areal extent of glaciers on a subgrid scale.
Jacob, Daniela, Kotlarski, Sven, Paul, Frank, Podzun, Ralf   +3 more
core  

Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)

Drug Testing and Analysis, EarlyView.
As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper, Gregor Fusshöller, Mario Thevis   +2 more
wiley   +1 more source

Recent glacier mass balance and area changes in the Kangri Karpo Mountains from DEMs and glacier inventories

, 2018
. Due to the influence of the Indian monsoon, the Kangri Karpo Mountains in the south-east of the Tibetan Plateau is in the most humid and one of the most important and concentrated regions containing maritime (temperate) glaciers.
Kun-peng Wu, Shi-yin Liu, Zong-li Jiang, Junli Xu, Junfeng Wei, Wanqin Guo   +5 more
semanticscholar   +1 more source