Results 101 to 110 of about 1,674,137 (304)

The distribution of basal motion beneath a High Arctic polythermal glacier [PDF]

, 2003
The longitudinal pattern of surface velocity of a large, predominantly colds polythermal glacier (John Evans Glacier, Ellesmere Island, Canada) was measured over summer and winter periods.
Nienow, Peter W., Copland, L, Nienow, P, Bingham, RG, Sharp, M.J., Bingham, Robert George, Copland, L., Copland, Luke, Bingham, R.G., Sharp, Martin J., Sharp, MJ, Nienow, P., Bingham, Robert G.   +12 more
core   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

Future Retreat of Great Aletsch Glacier and Hintereisferner – application of a full-Stokes model to two valley glaciers in the European Alps [PDF]

The Cryosphere
We simulate the future evolution of two valley glaciers in the European Alps over the course of the 21st century. The model setup combines a numerical realization of full-Stokes ice dynamics coupled to a surface energy balance model forced with the ...
M. Rückamp, G. Cheng, G. Cheng, K. Gutjahr, M. Möller, P. K. E. Pellikka, P. K. E. Pellikka, C. Mayer   +7 more
doaj   +1 more source

Coherent scatterers detection: application over glacier terrain using TerraSAR-X time series data [PDF]

, 2011
This paper investigates the detection of Coherent Scatterers (CSs) in ice and glacier terrain by means of TerraSAR-X time series data in the test site of the Helheim Glacier in Greenland.
Maria J. Sanjuan-Ferrer, Hajnsek, Irena, Papathanassiou, Kostantinos P., Kostantinos P. Papathanassiou, Sanjuan-Ferrer, Maria J., Irena Hajnsek   +5 more
core   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Simulating climatic mass balance, seasonal snow development and associated freshwater runoff in the Kongsfjord basin, Svalbard (1980–2016)

Journal of Glaciology, 2018
The Kongsfjord basin in northwest Svalbard is the site of a number of interdisciplinary studies concerned with the effect of fresh water from seasonal snow and glacier melt on the physical and biological environment.
ANKIT PRAMANIK, WARD VAN PELT, JACK KOHLER, THOMAS V. SCHULER   +3 more
doaj   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Glacier mass variation and its effect on surface runoff in the Beida River catchment during 1957–2013

Journal of Glaciology, 2017
Using in-situ measured data from Qiyi Glacier, in combination with meteorological and run-off data from stations, a distributed degree-day model was developed for 631 investigated glaciers in the Beida River catchment to explore glacier mass change and ...
SHENG WANG, TANDONG YAO, LIDE TIAN, JIANCHEN PU   +3 more
doaj   +1 more source

A particle based simulation model for glacier dynamics [PDF]

, 2013
A particle-based computer simulation model was developed for investigating the dynamics of glaciers. In the model, large ice bodies are made of discrete elastic particles which are bound together by massless elastic beams.
Timonen, J., Moore, J. C., J. A. Åström, T. Zwinger, Astrom, J. A., D. Benn, J. C. Moore, Zwinger, T., Tallinen, T., T. Tallinen, T. I. Riikilä, Benn, D., J. Timonen, Riikila, T. I.   +13 more
core   +2 more sources

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source