Results 61 to 70 of about 1,597 (261)
Advanced Science, EarlyView.Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li +7 more
wiley +1 more source
Journal of Limnology, 2012 Due to global change affecting glaciers worldwide, glacial streams are seen as threatened environments deserving specific scientific interest. Glacial streams from the Coast Range and Rocky Mountains in British Columbia and at the border to Alberta were ...
Eugen Rott, Doris Gesierich
doaj +1 more source
High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State
American Journal of Botany, EarlyView.Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording +4 more
wiley +1 more source
« An Octopus / of ice » : stratigraphies d’un poème
Transatlantica, 2015 Fascinated by living and rock surfaces, and by their hidden depths, shaped by its multiple layers of discourse, “An Octopus,” the long poem Marianne Moore dedicated to the Mount Rainier glacier and national park at the beginning of the 1920s, invites to ...
Aurore Clavier
doaj +1 more source
American Journal of Botany, EarlyView.Abstract Premise The origin of endemic species in the European Alps is commonly attributed to the climatic oscillations of the Quaternary. Moehringia sect. Moehringia, with 12 of 15 species endemic to the Alps and mostly restricted to well‐known glacial refugia, is a prime system for investigating the diversification of a lineage originating in the ...
Joachim W. Kadereit +4 more
wiley +1 more source
American Journal of Community Psychology, EarlyView.Abstract US universities are built on stolen land and sustained through hierarchies of power that produce what migrant justice scholars name as b/order regimes. As institutions that claim to be sites of learning and inclusion, universities are fraught with contradictions as simultaneously sites of dispossession, exclusion, and control.
Sara L. Buckingham +1 more
wiley +1 more source
Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo +13 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley +1 more source
Results in Earth SciencesIn this study, we have investigated four glaciers, namely Zemu, Talung, Alukthang and Rathong within Kanchenjunga national park. This study evaluates physical and morphometric parameters (area, length, perimeter, area of accumulation zone, ablation zone ...
Soumik Saha +4 more
doaj +1 more source
BMEMat, EarlyView.ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning +10 more
wiley +1 more source