Results 71 to 80 of about 173,582 (301)

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Canada lynx occupancy and density in Glacier National Park

Journal of Wildlife Management, 2023
Alissa K. Anderson, J. Waller, D. Thornton   +2 more
semanticscholar   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

Significant changes of area, length and terminus of Sikkim Himalayan glaciers within the Kanchenjunga national park from 1990 - 2022

Results in Earth Sciences
In this study, we have investigated four glaciers, namely Zemu, Talung, Alukthang and Rathong within Kanchenjunga national park. This study evaluates physical and morphometric parameters (area, length, perimeter, area of accumulation zone, ablation zone ...
Soumik Saha, Biswajit Bera, Sumana Bhattacharjee, Nairita Sengupta, Mridul Barman   +4 more
doaj   +1 more source

Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal (Phoca vitulina) population

Acta Veterinaria Scandinavica, 2013
Background Brucella is a group of bacteria that causes brucellosis, which can affect population health and reproductive success in many marine mammals.
Hueffer Karsten, Gende Scott M, O’Hara Todd M   +2 more
doaj   +1 more source

Does Climate Risk Affect Employment Decisions? International Evidence

Business Strategy and the Environment, EarlyView.
ABSTRACT This study investigates the effect of climate risk on corporate employment decisions. Using a large sample from 41 countries, we find a positive association between climate risk and underinvestment in labor, notably manifesting as excessive employee layoffs.
Claude Francoeur, Faten Lakhal, Hamza Nizar, Zvi Singer   +3 more
wiley   +1 more source

Positional Relationship Between the Orbicularis Oculi and Zygomaticus Complex Muscles by Ultrasonography: New Anatomical Insights for Crow's Feet Injection

Clinical Anatomy, EarlyView.
ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao, Ji‐Hyun Lee, Kyung‐Seok Hu, Hee‐Jin Kim   +3 more
wiley   +1 more source

Titanium‐Catalyzed Diastereoselective Keto‐ and Iminonitrile Cyclizations

Chemistry – A European Journal, EarlyView.
The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Christoph Kern, Ritu Singh, Michael A. Unkrig‐Bau, Lukas Jakob, Jan Streuff   +4 more
wiley   +1 more source

Introducing a glacier forefield monitoring site network to understand succession in the Northern Limestone Alps [PDF]

Web Ecology
Since the end of the Little Ice Age (ca. 1855), glaciers retreated in the Alps, leaving new ground for genuine primary succession. The patterns and processes of glacier forefield succession have been studied globally for decades.
I. Kühn, I. Kühn, C. Hecht, C. Hecht, U. Herzschuh, D. Scherler   +5 more
doaj   +1 more source

Clathrate hydrate crystallization

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Clathrate hydrate crystallization has been an area of interest to chemical engineers from the point of view of crystal structure, thermophysical properties, phase equilibria, kinetics, industrial applications, and environmental (climate change) implications.
Peter Englezos
wiley   +1 more source