Results 91 to 100 of about 8,044,192 (299)

Spectral roughness of glaciated bedrock geomorphic surfaces: Implications for glacier sliding [PDF]

, 2000
A microroughness meter (MRM) was used to measure the high-frequency roughness of a number of geomorphic surfaces in the forefield of Glacier de Tsanfleuron, Switzerland.
Martin J. Siegert, Danny McCarroll, Hubbard, B., McCarroll, D., Bryn Hubbard, Siegert, M. J.   +5 more
core   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Increased mass loss of glaciers in Volcán Domuyo (Argentinian Andes) between 1962 and 2020, revealed by aerial photos and satellite stereo imagery

Journal of Glaciology, 2023
We present geodetic mass-balance estimates for ten glaciers (22.6 ± 1.1 km2) around Volcán Domuyo between 1962 and 2020 (and 46 glaciers covering 29 ± 1.5 km2 between 1984 and 2020), derived from airborne, ASTER and Pléiades imagery.
Daniel Falaschi, Etienne Berthier, Joaquín M. C. Belart, Claudio Bravo, Mariano Castro, Marcelo Durand, Ricardo Villalba   +6 more
doaj   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Modelling glacier-bed overdeepenings and possible future lakes for the glaciers in the Himalaya—Karakoram region

Annals of Glaciology, 2016
Surface digital elevation models (DEMs) and slope-related estimates of glacier thickness enable modelling of glacier-bed topographies over large ice-covered areas.
A. Linsbauer, H. Frey, W. Haeberli, H. Machguth, M.F. Azam, S. Allen   +5 more
doaj   +1 more source

Glacier projections sensitivity to temperature-index model choices and calibration strategies

Annals of Glaciology, 2023
The uncertainty of glacier change projections is largely influenced by glacier models. In this study, we focus on temperature-index mass-balance (MB) models and their calibration.
Lilian Schuster, David R. Rounce, Fabien Maussion   +2 more
doaj   +1 more source

The distribution of basal motion beneath a High Arctic polythermal glacier [PDF]

, 2003
The longitudinal pattern of surface velocity of a large, predominantly colds polythermal glacier (John Evans Glacier, Ellesmere Island, Canada) was measured over summer and winter periods.
Nienow, Peter W., Copland, L, Nienow, P, Bingham, RG, Sharp, M.J., Bingham, Robert George, Copland, L., Copland, Luke, Bingham, R.G., Sharp, Martin J., Sharp, MJ, Nienow, P., Bingham, Robert G.   +12 more
core   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Hydrological response to climate change in a glacierized catchment in eastern Tien Shan, Central Asia

Journal of Hydrology: Regional Studies
Study region: The headwaters of Urumqi River basin located in eastern Tien Shan Study focus: Glacier shrinkage in recent decades has caused the volume and timing of glacier-fed streamflow to change, which in turn has significantly impacted the water ...
Yufeng Jia, Zhongqin Li, Hongkai Gao, Shengjie Wang, Meiping Sun, Puyu Wang   +5 more
doaj   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

Advanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo, Yu He, Shuyao Li, Haoyu Guan, Ruili Cui, Yu Shi, Zhongwen Jiang, Siyu Wang, Xuan Li, Jiyuan Li, Mei Hu, Yupeng Zhou, Beisha Tang, Yanyan Zhang, Zhaobing Gao, Yu Zhou, Zhenhua Liu, Ping Li   +17 more
wiley   +1 more source