Results 101 to 110 of about 922 (163)

TbpB^Y167A-Based Vaccine Can Protect Pigs against Glässer’s Disease Triggered by Glaesserella parasuis SV7 Expressing TbpB Cluster I

Pathogens, 2022
Glaesserella parasuis is the etiological agent of Glässer’s disease (GD), one of the most important diseases afflicting pigs in the nursery phase.
Simone Ramos Prigol, Rafaela Klein, Somshukla Chaudhuri, Gabriela Paraboni Frandoloso, João Antônio Guizzo, César Bernardo Gutiérrez Martín, Anthony Bernard Schryvers, Luiz Carlos Kreutz, Rafael Frandoloso   +8 more
doaj   +1 more source

Pharmacokinetic–Pharmacodynamic Cutoff Values for Doxycycline in Pigs to Support the Establishment of Clinical Breakpoints for Antimicrobial Susceptibility Testing

Journal of Veterinary Pharmacology and Therapeutics, Volume 48, Issue 4, Page 300-317, July 2025.
ABSTRACT This meta‐analysis provides a population model of doxycycline (DOXY) disposition in pigs for computation of PK/PD cutoff values corresponding to differing modalities of DOXY administration orally in pigs. This analysis enables establishment of specific clinical breakpoints for the development of antimicrobial susceptibility testing of DOXY in ...
Pierre‐Louis Toutain, Alain Bousquet‐Melou, Aude A. Ferran, Béatrice B. Roques, Jérôme R. E. del Castillo, Peter Lees, Siska Croubels, Eric Bousquet, Ludovic Pelligand   +8 more
wiley   +1 more source

Vaccine‐Induced Immune Thrombotic Thrombocytopenia Caused by Zoetis PR‐VAC PLUS in Pseudorabies Virus‐Free Danish Purebred Pigs

Veterinary Medicine and Science, Volume 11, Issue 2, March 2025.
Vaccine‐induced immune thrombotic thrombocytopenia (VITT), a novel syndrome of adverse events following adenovirus vector COVID‐19 vaccines, was observed after vaccination with Zoetis PR‐VAC PLUS. This resulted in 100% morbidity in PRV‐free Danish pure breeders from Danish Genetics Co., causing severe pulmonary oedema, gastric ulcers, haemorrhagic ...
Chien‐Cheng Chen
wiley   +1 more source

Integration of Methylation and Gene Expression Deciphered Candidate Biomarkers DAB2IP and SMYD3 in Delayed Encephalopathy After Carbon Monoxide Poisoning

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
By integrating DNA methylation and gene expression from patients with delayed encephalopathy after carbon monoxide poisoning (DEACMP), this study identified DAB2IP and SMYD3 as candidate genes potentially involved in DEACMP pathogenesis. Additionally, further evidence for their potential as DEACMP targets was provided through pyrosequencing and DEACMP ...
Hongyi Yan, Ding Yuan, Yan Zhang, Haihua Luo, Pinpin Jiang, Yapeng Zhang, Yue Wu, Linlin Hou, Yue Cheng, Fang Yang, Yuqi Du, Huanzhou Zhu, Linshuang Zhao, Yi Li, Yong Jiang, Yanxia Gao   +15 more
wiley   +1 more source

Characterization and protective activity of monoclonal antibodies directed against Fe (3+) ABC transporter substrate-binding protein of Glaesserella parasuis

Veterinary Research, 2021
Glässer’s disease is caused by the agent Glaesserella parasuis and is difficult to prevent and control. Candidate screening for subunit vaccines contributes to the prevention of this disease. Therefore, in this study, the inactivated G.
Kexin Zhu, Dong Yu, Jiahui An, Yufeng Li
doaj   +1 more source

Use of Subtherapeutic Tylvalosin Against Mycoplasma hyopneumoniae: Implications For Respiratory Microbiome Dysbiosis and Swine Lung Health

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Enzootic pneumonia (EP) caused by Mycoplasma hyopneumoniae (M. hyopneumoniae) has a significant impact on swine production. Subtherapeutic exposures of tylvalosin in swine, often due to inconsistent dosing in feed or water, promote antimicrobial resistance.
Leonardo Teófilo Toledo, Richard Costa Polveiro, Caio Augustus Diamantino, Gustavo Manoel Rigueira Simão, Carlos Eduardo Real Pereira, Eduardo de Freitas Costa, Maria Aparecida Scatamburlo Moreira, Fernanda Simone Marks, Orhan Sahin   +8 more
wiley   +1 more source

Analysis of Virulence and Drug Resistance of Glaesserella parasuis Serotype 2

Guangdong nongye kexue, 2023
【Objective】Glaesserella parasuis (GPS) is the pathogen that causes Gl?sser's disease in pigs. It is one of the most serious bacterial pathogens that harm pig industry. There are many serotypes of this bacterium, and the crossprotection between different serotypes is weak.
Zhifang WANG, Yindi XU, Wenhao ZHU, Wenqiang JIAO, Qingxian ZHANG, Haili LI, Feng XU, Keling WANG   +7 more
openaire   +1 more source

Evaluation of the recombinant proteins RlpB and VacJ as a vaccine for protection against Glaesserella parasuis in pigs

BMC Veterinary Research, 2020
Background Glaesserella parasuis, the causative agent of Glӓsser’s disease, is widespread in swine globally resulting in significant economic losses to the swine industry.
Samantha J. Hau, Shi-Lu Luan, Crystal L. Loving, Tracy L. Nicholson, Jinhong Wang, Sarah E. Peters, David Seilly, Lucy A. Weinert, Paul R. Langford, Andrew N. Rycroft, Brendan W. Wren, Duncan J. Maskell, Alexander W. Tucker, Susan L. Brockmeier, on behalf of the BRaDP1T Consortium   +14 more
doaj   +1 more source

Molecular characterization of Glaesserella parasuis strains isolated from North America, Europe and Asia by serotyping PCR and LS-PCR

Veterinary Research, 2021
Glaesserella parasuis strains were characterized by serotyping PCR, vtaA virulence marker Leader Sequence (LS)-PCR, clinical significance, and geographic region. Overall, the serovars 4, 5/12, 7, 1, and 13 were the most commonly detected.
Nubia Macedo, Marcelo Gottschalk, Katrin Strutzberg-Minder, Chao Nguyen Van, Lijun Zhang, Geng Zou, Rui Zhou, Thaire Marostica, Maria Jose Clavijo, Alexander Tucker, Virginia Aragon   +10 more
doaj   +1 more source

Comprehensive lung microbial gene and genome catalogs assist the mechanism survey of Mesomycoplasma hyopneumoniae strains causing pig lung lesions

iMeta, Volume 3, Issue 6, December 2024.
In this study, we utilized 744 metagenomic sequencing data from lower respiratory tract microbial samples of 675 well‐phenotyped pigs across five cohorts. From these, we constructed a microbial gene catalog containing 10,031,593 nonredundant genes and 356 metagenome‐assembled genomes (MAGs), which were further clustered into 256 species‐level genome ...
Jingquan Li, Fei Huang, Yunyan Zhou, Tao Huang, Xinkai Tong, Mingpeng Zhang, Jiaqi Chen, Zhou Zhang, Huipeng Du, Zifeng Liu, Meng Zhou, Yiwen Xiahou, Huashui Ai, Congying Chen, Lusheng Huang   +14 more
wiley   +1 more source