Dietary baicalin supplementation enhances growth performance in fattening Hu sheep via dual modulation of immunity and gastrointestinal microbiome-metabolic crosstalk [PDF]
Journal of Animal Science and BiotechnologyBackground Baicalin is a bioactive flavonoid from Scutellaria baicalensis Georgi with antioxidant, anti‑inflammatory and antibacterial properties. However, its bitter taste and susceptibility to ruminal degradation limit its practical use in mammals ...
Di Ding +8 more
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The Pharmacological Efficacy of Baicalin in Inflammatory Diseases
International Journal of Molecular Sciences, 2023 Baicalin is one of the most abundant flavonoids found in the dried roots of Scutellaria baicalensis Georgi (SBG) belonging to the genus Scutellaria. While baicalin is demonstrated to have anti-inflammatory, antiviral, antitumor, antibacterial, anticonvulsant, antioxidant, hepatoprotective, and neuroprotective effects, its low hydrophilicity and ...
Boayu Zhao, Jianguo Wang, Chenxu Zhao
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Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage [PDF]
Frontiers in Pharmacology, 2021 Intracerebral hemorrhage (ICH) is a subtype of stroke characterized by high mortality and disability rates. To date, the exact etiology of ICH-induced brain injury is still unclear.
Lining Duan +17 more
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Baicalin inhibits infectious bronchitis virus replication via MAVS-dependent interferon-β upregulation and mitochondrial function preservation [PDF]
Scientific ReportsThe inhibitory effect of baicalin on infectious bronchitis virus (IBV) replication is closely related to expression of the mitochondrial antiviral signaling protein (MAVS) in chicken embryonic kidney (CEK) cells.
Jiongjie He +3 more
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The Antiviral Effect of Baicalin on Enterovirus 71 In Vitro
Viruses, 2015 Baicalin is a flavonoid compound extracted from Scutellaria roots that has been reported to possess antibacterial, anti-inflammatory, and antiviral activities. However, the antiviral effect of baicalin on enterovirus 71 (EV71) is still unknown.
Xing Fei, Shi Weifeng
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Journal of Bone Oncology, 2022 Baicalin, a flavonoid derivative, exerts antitumor activity in a variety of neoplasms. However, whether baicalin exerts antitumor effects on osteosarcoma cells remains to be elucidated. In this study, treatment with baicalin reduced the proliferation and
He Pang +7 more
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Protective effect of baicalin against cognitive memory dysfunction after splenectomy in aged rats and its underlying mechanism [PDF]
Journal of Integrative Neuroscience, 2020 Postoperative cognitive dysfunction is a common neurological complication, characterized by impaired learning and memory, that occurs after anesthesia and surgery, especially in elderly patients. The traditional Chinese medicine baicalin is known to have
Jian-Nan Zhang +4 more
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BMC Complementary Medicine and Therapies, 2022 Background Baicalin is a generally available flavonoid with potent biological activity. The present study aimed to assess the underlying mechanism of baicalin in treatment of atherosclerosis (AS) with the help of network pharmacology, molecular docking ...
Mingshuang Li, Conglin Ren
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Baicalin protects the cardiomyocytes from ER stress-induced apoptosis: inhibition of CHOP through induction of endothelial nitric oxide synthase. [PDF]
PLoS ONE, 2014 Baicalin, the main active ingredient of the Scutellaria root, exerts anti-oxidant and anti-apoptotic effects in cardiovascular diseases. However, the therapeutic mechanism of baicalin remains unknown. Cultured neonatal rat cardiomyocytes were pre-treated
Mingzhi Shen +14 more
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Antiviral Properties of Baicalin: a Concise Review [PDF]
Revista Brasileira de Farmacognosia, 2021 Baicalin is one of the bioactive flavonoid glycosides isolated from the dried root of Scutellaria baicalensis Georgi, Lamiaceae, with antiviral properties. In recent years, the antiviral activity of baicalin has been widely investigated to explore its molecular mechanism of action.
Kunwei Li +7 more
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