Results 11 to 20 of about 9,549 (183)

Inhibitory effect of baicalin on Streptococcus mutans UA159 in vitro

open access: yes口腔疾病防治, 2021
Objective To investigate the inhibitory effect of baicalin on Streptococcus mutans UA159 in vitro.Methods The minimum inhibitory concentration (MIC) of baicalin on Streptococcus mutans UA159 was determined by the liquid multiple dilution method combined ...
WU Ju, WANG Ling, LIU Xingrong
doaj   +1 more source

Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways

open access: yesMolecules, 2023
Baicalin is an active ingredient extracted from the Chinese medicine Scutellaria and has many beneficial effects. Pulmonary interstitial and alveolar edema are common symptoms of an acute lung injury (ALI).
Bingyu Shen   +6 more
doaj   +1 more source

Facilitating Granule Cell Survival and Maturation in Dentate Gyrus With Baicalin for Antidepressant Therapeutics

open access: yesFrontiers in Pharmacology, 2020
Baicalin isolated from Scutellaria baicalensis possesses antidepressant abilities through its relation to hippocampal neurogenesis. Current research has found that baicalin can promote the proliferation of hippocampal granule cells, however, the detailed
Fan Zhao   +10 more
doaj   +1 more source

Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway

open access: yesPharmaceutical Biology, 2022
Context Baicalin, a flavonoid extracted from radix scutellariae, possesses various pharmacological effects, including protective effects on renal interstitial fibrosis (RIF), but its possible role and mechanisms have not been fully elucidated.Objective ...
Hui Wang, Qingtao Jiang, Lizhu Zhang
doaj   +1 more source

Antiviral effect of baicalin on Marek’s disease virus in CEF cells

open access: yesBMC Veterinary Research, 2020
Background Baicalin, the main metabolic component of Scutellaria baicalensis Georgi, has various pharmacological properties including anti-inflammatory, anti-oxidant, anti-apoptotic, anti-bactericidal and anti-viral.
Fan Yang   +5 more
doaj   +1 more source

Baicalin Promotes Mammary Gland Development via Steroid-Like Activities

open access: yesFrontiers in Cell and Developmental Biology, 2021
Baicalin, the main flavonoid component extracted from Scutellaria roots, has a variety of biological activities and is therefore used in the treatment of many kinds of diseases.
Weizhen Chen   +10 more
doaj   +1 more source

Effects of Baicalin on Alopecia and the Associated Mechanism

open access: yesBioMed Research International, 2022
The aim of the present study was to explore the potential pharmacological mechanism of baicalin by combining network pharmacology prediction and the experimental verification of alopecia. Networks of baicalin‐associated targets and alopecia‐related genes were constructed using the STRING database.
Liping Chen   +4 more
openaire   +2 more sources

Baicalin Ameliorates Inflammatory Response in a Mouse Model of Rhinosinusitis via Regulating the Treg/Th17 Balance

open access: yesEar, Nose & Throat Journal, 2022
Objective: Rhinosinusitis is a global health problem affecting millions of people around the world. Baicalin is a bioactive compound isolated from medicinal plant Scutellaria baicalensis Georgi.
Ming Yang BM   +8 more
doaj   +1 more source

Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Background Myocardial ischemia is the main reason for ischemic heart disease. Baicalin is a plant-derived flavonoid with cardio-protective activity.
Hailiang Yu, Bin Chen, Qi Ren
doaj   +1 more source

Chemoprotective effect of baicalin against cyclophosphamide induced ovarian toxicity in mice via inhibition of TGF-β

open access: yesHeliyon, 2023
Ovarian toxicity is most common gynecologically related malignancy, arising for most cases owing to the advanced stage of diagnosis. The aim of the current study was to explore the anticancer potential of baicalin against cyclophosphamide (CP) induced ...
Xuefeng Li   +3 more
doaj   +1 more source

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