Results 21 to 30 of about 11,830 (227)

Effects of Baicalin on Alopecia and the Associated Mechanism

open access: yesBioMed Research International, 2022
The aim of the present study was to explore the potential pharmacological mechanism of baicalin by combining network pharmacology prediction and the experimental verification of alopecia. Networks of baicalin‐associated targets and alopecia‐related genes were constructed using the STRING database.
Liping Chen   +4 more
openaire   +2 more sources

Chemoprotective effect of baicalin against cyclophosphamide induced ovarian toxicity in mice via inhibition of TGF-β

open access: yesHeliyon, 2023
Ovarian toxicity is most common gynecologically related malignancy, arising for most cases owing to the advanced stage of diagnosis. The aim of the current study was to explore the anticancer potential of baicalin against cyclophosphamide (CP) induced ...
Xuefeng Li   +3 more
doaj   +1 more source

Baicalin attenuates lipopolysaccharide-induced pro-inflammatory cytokine expression in murine macrophage cell line RAW264.7 through miR-124-STAT3 axis

open access: yesEuropean Journal of Inflammation, 2018
Baicalin, a flavonoid isolated from Scutellaria baicalensis Georgi, has shown a wide range of anti-inflammatory, antioxidative, antiviral, and antitumor properties.
Bin Tang   +4 more
doaj   +1 more source

Baicalin Induces Apoptosis in SW620 Human Colorectal Carcinoma Cells in Vitro and Suppresses Tumor Growth in Vivo

open access: yesMolecules, 2012
In the United States, colorectal cancer (CRC) is the second most frequent malignancy and the fourth most common cause of cancer death. Baicalin, a flavone derivative isolated and purified from the dry root of Scutellaria, was assessed for its antitumor ...
Yi-Shiuan Tzeng   +3 more
doaj   +1 more source

Baicalin regulates macrophages polarization and alleviates myocardial ischaemia/reperfusion injury via inhibiting JAK/STAT pathway

open access: yesPharmaceutical Biology, 2020
Context Baicalin is an active compound which demonstrates cardioprotection effects against myocardial ischaemia/reperfusion injury (MI/RI). Objective To investigate how baicalin protects against myocardial injury and to explore its potential mechanism ...
Ming Xu, XiaoYong Li, Laichun Song
doaj   +1 more source

Protective effects of baicalin magnesium on non-alcoholic steatohepatitis rats are based on inhibiting NLRP3/Caspase-1/IL-1β signaling pathway

open access: yesBMC Complementary Medicine and Therapies, 2023
Baicalin magnesium is a water-soluble compound isolated from the aqueous solution by Scutellaria baicalensis Georgi. Preliminary experiments have demonstrated that baicalin magnesium can exert protective effects against acute liver injury in rats induced
Xiulu Guan   +8 more
doaj   +1 more source

Data of Baicalin

open access: yes, 2020
Results 1. Effects of Baicalin on cell viability and LDH production Note: RAW264.7 cells viability——RAW细菌感染细胞活性 H9 cells viability——H9细菌感染细胞活性 1——control group;2——S. typhimurium group;3,4,5——S.
Ling, Zhang
core   +1 more source

Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice

open access: yesDiabetes & Vascular Disease Research, 2020
Background: NLR family pyrin domain containing 3 (NLRP3) inflammasome has been implicated in the development of atherosclerosis and several studies have suggested that inhibiting NLRP3 inflammasome could be a potential therapeutic approach to treat ...
Jingfei Zhao   +4 more
doaj   +1 more source

Baicalin protects neonatal rat brains against hypoxic-ischemic injury by upregulating glutamate transporter 1 via the phosphoinositide 3-kinase/protein kinase B signaling pathway

open access: yesNeural Regeneration Research, 2017
Baicalin is a flavonoid compound extracted from Scutellaria baicalensis root. Recent evidence indicates that baicalin is neuroprotective in models of ischemic stroke.
Zhi-qing Zhou   +7 more
doaj   +1 more source

Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study

open access: yesVeterinary Research, 2022
Staphylococcus saprophyticus is frequently involved in various difficult-to-treat infections due to the formation of biofilms. To identify useful antibiofilm strategies, this study explored the efficacy and mechanism of baicalin in enhancing the ability ...
Jinli Wang   +12 more
doaj   +1 more source

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