Results 151 to 160 of about 922 (163)
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Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China
Research in Veterinary Science, 2023Glaesserella parasuis (G. parasuis) is a part of the normal upper respiratory microbiota of healthy swine. In many studies, the serovars 1, 4, 5, and 12 of G. parasuis are considered to be highly virulent and its serovars 3, 6, 7, 9, and 11 are considered to be non-virulent. Until now, researchers have found that non-virulent strains of G.
Ping, Yan +11 more
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Journal of Medical Microbiology, 2023
Introduction. Various plasmid-mediated resistance genes have been reported in Glaesserella parasuis , but little is known about their global distribution features, evolution pattern and spread. Gap Statement.
Huarun Sun +12 more
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Introduction. Various plasmid-mediated resistance genes have been reported in Glaesserella parasuis , but little is known about their global distribution features, evolution pattern and spread. Gap Statement.
Huarun Sun +12 more
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PK/PD modelling of enrofloxacin againstGlaesserella parasuisinfection in pigs
Journal of Veterinary Pharmacology and Therapeutics, 2022AbstractA pharmacokinetic/pharmacodynamic (PK/PD) model was developed to optimize the dosing regimen of enrofloxacin (EN) againstGlaesserella parasuisin pigs. EN (2.5 mg/kg) was administered intramuscularly to eight healthy pigs and eight pigs that were experimentally infected withG. parasuisSW124.
Bo Yang +7 more
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An auto-excision system for rapid and efficient genetic manipulation in Glaesserella parasuis
Microbiological ResearchSite-specific recombination systems are widely used in bacterial gene editing due to their precision and efficiency. However, traditional gene editing methods often require labor-intensive plasmid construction and multiple transformation steps, which can be time-consuming and inefficient.
Jing Xiao +3 more
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Neuraminidase and pH responsive nano-drug against resistant Glaesserella parasuis
International Journal of Biological MacromoleculesGlaesserella parasuis (GPS) infection leads to significant economic losses in livestock, with antibiotic resistance exacerbating the issue. The lengthy development cycle of new drugs further complicates timely intervention. Neuraminidase, a virulence factor of GPS, plays a critical role in infection progression.
Zhixin, Lei +4 more
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Microbial Pathogenesis
QseC is a membrane sensor kinase that enables bacteria to perceive autoinducers -3, adrenaline, and norepinephrine to initiate downstream gene transcription. In this study, we found that the QseC protein of Glaesserella parasuis can serve as an effective antigen to activate the host's immune response.
Xuefeng, Yan +9 more
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QseC is a membrane sensor kinase that enables bacteria to perceive autoinducers -3, adrenaline, and norepinephrine to initiate downstream gene transcription. In this study, we found that the QseC protein of Glaesserella parasuis can serve as an effective antigen to activate the host's immune response.
Xuefeng, Yan +9 more
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Deletion of Glaesserella parasuis nanA promotes apoptosis by inhibiting PINK1/Parkin pathway
International Journal of Biological MacromoleculesGlaesserella parasuis (G. parasuis) is the primary pathogen responsible for Glasser's disease in large-scale pig farms. It causes annual mortality rates of 10-20% in weaned piglets due to meningitis, serositis, and sudden death syndrome. The rapid spread of multidrug-resistant strains has reduced the cure rate of macrolide antibiotics and other drugs ...
Yaqin, Liu +4 more
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Multi-epitope vaccines Xlc and Ddc against Glaesserella parasuis infection in mice
Veterinary MicrobiologyGlaesserella parasuis (synonym Haemophilus parasuis) is the pathogenic agent of Glässer's disease and causes huge economic losses in the world's swine industry. Glaesserella parasuis (G. parasuis) can be divided into 15 serotypes, and the cross-protection effect of existing vaccines is not satisfactory.
Lu Dai +9 more
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Strain-dependent interactions of Streptococcus suis and Glaesserella parasuis in co-culture.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2023Streptococcus suis (S. suis) and Glaesserella parasuis (G. parasuis) are ubiquitous colonizers of swine tonsils that can cause systemic disease and death, under undefined conditions. It is not known, however, whether these 2 species interact during initial infection.
Adina R, Bujold +3 more
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