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Influence of genomic variations on glanders serodiagnostic antigens using integrative genomic and transcriptomic approaches [PDF]

open access: yesFrontiers in Veterinary Science, 2023
Glanders is a highly contagious and life-threatening zoonotic disease caused by Burkholderia mallei (B. mallei). Without an effective vaccine or treatment, early diagnosis has been regarded as the most effective method to prevent glanders transmission ...
Philippe Charron   +9 more
doaj   +2 more sources

Knowledge, awareness and perception about equine glanders among veterinarians and medical professionals in India [PDF]

open access: yesFrontiers in Veterinary Science
Glanders is a highly infectious and notifiable disease of equines that occurs due to Burkholderia mallei. In India, glanders re-emerged in 2006 and thereafter regular outbreaks have been reported in various states (n = 14). Frequent and prolonged contact
Ana Raj   +5 more
doaj   +2 more sources

One Health surveillance approaches for melioidosis and glanders: The Malaysian perspective [PDF]

open access: yesFrontiers in Veterinary Science, 2022
The One Health concept was initiated to promote the integration of human, animal, and environmental ecosystems into healthcare to ensure effective control and the sustainable governance of multifaceted health matters.
Vanitha Mariappan   +8 more
doaj   +2 more sources

Glanders: An ancient and emergent disease with no vaccine or treatment on site. [PDF]

open access: yesPLoS Neglected Tropical Diseases
Glanders is a highly contagious and potentially fatal zoonotic disease that primarily affects equines but can also infect humans. Caused by the bacterium Burkholderia mallei, the disease is characterized by nodular lesions in the lungs and ulcerations of
Alfredo G Torres
doaj   +2 more sources

Assessment of the Virulence of the Burkholderia mallei Strain BAC 86/19 in BALB/c Mice [PDF]

open access: yesMicroorganisms, 2023
Burkholderia mallei is an aerobic, Gram-negative, non-motile bacillus. As an obligate mammalian pathogen, it primarily affects solipeds. Although rarely transmitted to humans, the disease it causes, glanders, is classified as a zoonosis.
Emanuelle Baldo Gaspar   +12 more
doaj   +2 more sources

Clinical and Molecular Characterization of Human Burkholderia mallei Infection, Brazil [PDF]

open access: yesEmerging Infectious Diseases
We report a case of Burkholderia mallei causing glanders in a 73-year-old patient from the Northeast Region of Brazil. The patient was hospitalized with severe pneumonia. PCR and genomic sequencing confirmed B. mallei in pleural drainage.
Kleber G. Luz   +15 more
doaj   +2 more sources

Glanders: Historical military use and potential bioterrorism concern [PDF]

open access: yesOpen Veterinary Journal
Burkholderia mallei, the etiological agent of glanders, is a zoonotic bacterium primarily affecting equines and occasionally humans. Although rare today, it remains endemic in certain regions and poses a potential threat to both animal and public health.
Mohammad Sukmanadi   +17 more
doaj   +2 more sources

Melioidosis vaccines: recent advances and future directions [PDF]

open access: yesFrontiers in Immunology
Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a severe infectious disease that is responsible for a significant amount of morbidity and mortality in endemic areas.
Sineenart Sengyee   +6 more
doaj   +2 more sources

Efficacy of finafloxacin in a murine model of inhalational glanders [PDF]

open access: yesFrontiers in Microbiology, 2022
Burkholderia mallei, the causative agent of glanders, is principally a disease of equines, although it can also infect humans and is categorized by the U.S. Centers for Disease Control and Prevention as a category B biological agent.
Kay B. Barnes   +7 more
doaj   +2 more sources

A Review of Glanders Regarded Iraq and Surrounding Countries [PDF]

open access: yesBasrah Journal of Veterinary Research, 2022
Glanders caused by Burkholderia mallei infected mainly the Equidae and it is really fatal zoonosis. It was known since ancient times. The horses, mules, and donkeys can get infection by skin abrasion, and during direct contact between animals or with ...
Ali Hmood, Mohammed Al-Amery
doaj   +1 more source

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