Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei [PDF]
Burkholderia pseudomallei and Burkholderia mallei are closely related Gram-negative bacteria responsible for the infectious diseases melioidosis and glanders, respectively.
Natalie Lazar Adler +2 more
exaly +6 more sources
Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate-binding pocket. [PDF]
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Okada U, Murakami S.
europepmc +2 more sources
Hospital-Based Cross-Sectional Study of <i>Burkholderia pseudomallei</i> Seroreactivity Among Febrile Patients in Northernmost Vietnam: Near-Neighbor Bloodstream Isolates, Environmental Correlates, and Spatial Clustering. [PDF]
Abstract Melioidosis is a potentially fatal tropical disease caused by the environmentally mediated bacterium, Burkholderia pseudomallei. In Vietnam, melioidosis is not nationally reportable and little is known regarding its epidemiology and distribution in the northernmost mountainous provinces.
Metrailer MC +14 more
europepmc +2 more sources
Genomic diversity and clade clustering of Burkholderia pseudomallei and B. thailandensis prophages with soil-derived phages [PDF]
Summary: Most studies on bacteriophages (phages) of the Gram-negative bacterium Burkholderia pseudomallei rely on in silico predictions and thus underestimate the true diversity of phages.
Patoo Withatanung +10 more
doaj +2 more sources
Shotgun metagenome sequencing and informatics can accurately form a metagenome-assembled genome (MAG) of the bacterial tier 1 select agent Burkholderia pseudomallei for rapid public health response events [PDF]
Shotgun metagenomics, when sufficient read depth exists for each taxon, enables capturing metagenome-assembled genomes (MAGs) directly from a microbial community.
Gregory A. Sprenger +4 more
doaj +2 more sources
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is increasingly used for rapid bacterial identification. Studies of Burkholderia pseudomallei identification have involved small isolate numbers drawn from a ...
Direk Limmathurotsakul +2 more
exaly +2 more sources
BackgroundBurkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. The global burden and distribution of melioidosis is poorly understood, including in the Caribbean. B.
Carina M Hall, , Chandler Roe
exaly +2 more sources
T6SS-5 and the cGAS-STING pathway in Burkholderia pseudomallei infection and immunity
Burkholderia pseudomallei is a causative agent of melioidosis that can infect humans and animals in endemic countries, specifically in Southeast Asia and tropical Australia. A fundamental component for the pathogenesis of Burkholderia pseudomallei is the
Noreafifah Semail +6 more
doaj +1 more source
Burkholderia pseudomallei (B. pseudomallei) is the etiologic agent of melioidosis. The aim of this study was to establish a SuperSpectrum of B. pseudomallei in Hainan and evaluate its application value in the rapid identification of clinical isolates of ...
M.H. Huang, H. Wu, L.L. Liu, X.M. Wang
doaj +1 more source
The Burkholderia pseudomallei phylogenetic cluster includes B. pseudomallei, B. mallei, B. thailandensis, B. oklahomensis, B. humptydooensis and B. singularis. Regarded as the only pathogenic members of this group, B. pseudomallei and B. mallei cause the
Sujintana Janesomboon +12 more
doaj +1 more source

