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Accurate identification of pathogens with biowarfare importance requires detection tools that specifically differentiate them from near-neighbor species. Burkholderia pseudomallei, the causative agent of a fatal disease melioidosis, is one such biothreat
Bhavani V Peddayelachagiri +5 more
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Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders. [PDF]
Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both
Dina A Moustafa +7 more
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Systemic melioidosis with prostatic abscess
Melioidosis is an infectious disease caused by the Gram-negative bacteria Burkholderia pseudomallei. The organism is a soil saprophyte and humans acquire infection via percutaneous inoculation through a breach in the skin.
F. S. Makeen +4 more
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Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B.
Heather P McLaughlin +2 more
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Burkholderia pseudomallei, the founding member of the B. pseudomallei complex (Bpc), is a biothreat agent and causes melioidosis, a disease whose treatment mainly relies on ceftazidime and meropenem. The concern is that B.
Nawarat Somprasong +7 more
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Melidiosis is a life-threatening infectious disease, and the causative organism is Burkholderia pseudomallei. It occurs as an environmental saprophyte in endemic regions of northern Australia and Southeast Asia.
Raju Iyengar +2 more
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An unusual case of primary melioidotic prostatic abscess complicated by perianal abscess
Burkholderia pseudomallei is recognized to cause severe and fatal infections. Most of the infections caused by this facultative intracellular gram-negative bacterium are pneumonia, soft tissue, genito-urinary and central nervous system infection.
Y.C. Chee, Y.N. Chee
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Efflux Pump-mediated Drug Resistance in Burkholderia
Several members of the genus Burkholderia are prominent pathogens. Infections caused by these bacteria are difficult to treat because of significant antibiotic resistance.
Nicole L Podnecky +4 more
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Diverse Burkholderia Species Isolated from Soils in the Southern United States with No Evidence of B. pseudomallei. [PDF]
The global distribution of the soil-dwelling bacterium Burkholderia pseudomallei, causative agent of melioidosis, is poorly understood. We used established culturing methods developed for B.
Carina M Hall +11 more
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Bacterial persistence due to antibiotic tolerance is a critical aspect of antibiotic treatment failure, disease latency, and chronic or reemergent infections.
William Charles Nierman +2 more
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