Burkholderia pseudomallei and melioidosis
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of tropical and subtropical regions globally. Modelled estimates of the global burden predict that melioidosis remains vastly under-reported, and a call has been made for it to be recognized as a neglected tropical disease by the World Health Organization.
Ella M. Meumann +4 more
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The Burkholderia pseudomallei intracellular ‘TRANSITome’ [PDF]
AbstractProkaryotic cell transcriptomics has been limited to mixed or sub-population dynamics and individual cells within heterogeneous populations, which has hampered further understanding of spatiotemporal and stage-specific processes of prokaryotic cells within complex environments.
Yun Heacock-Kang +11 more
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Misidentification of Burkholderia pseudomallei, China [PDF]
We report a case of melioidosis in China and offer a comparison of 5 commercial detection systems for Burkholderia pseudomallei. The organism was misidentified by the VITEK 2 Compact, Phoenix, VITEK mass spectrometry, and API 20NE systems but was eventually identified by the Bruker Biotyper system and 16S rRNA sequencing.
Bin Wu +6 more
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Melioid meningitis: First reported case of Burkholderia pseudomallei meningitis In Colombia
Human melioidosis is a serious infectious disease commonly known by being endemic in southeast Asia and northern Australia. It is caused by Burkholderia pseudomallei a non-spore forming gram negative bacillus.
Santiago Sanchez-Pardo +4 more
doaj +1 more source
Current Advances in Burkholderia Vaccines Development
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang +2 more
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A Quadruplex Real-Time PCR Assay for the Rapid Detection and Differentiation of the Most Relevant Members of the B. pseudomallei Complex: B. mallei, B. pseudomallei, and B. thailandensis. [PDF]
The Burkholderia pseudomallei complex classically consisted of B. mallei, B. pseudomallei, and B. thailandensis, but has now expanded to include B. oklahomensis, B. humptydooensis, and three unassigned Burkholderia clades.
Chinn-Woan Lowe +11 more
doaj +1 more source
Survival of Burkholderia pseudomallei in Water [PDF]
AbstractBackgroundThe ability ofBurkholderia pseudomalleito survive in water likely contributes to its environmental persistence in endemic regions. To determine the physiological adaptations which allowB. pseudomalleito survive in aqueous environments, we performed microarray analyses ofB.
Woods Donald E +2 more
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A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection. [PDF]
Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly infectious and broad-spectrum antibiotic resistant.
Beth A Bachert +11 more
doaj +1 more source
Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. [PDF]
Burkholderia pseudomallei and Burkholderia mallei are category B select agents and must be studied under BSL3 containment in the United States. They are typically resistant to multiple antibiotics, and the antibiotics used to treat B.
Sheryl L W Zajdowicz +5 more
doaj +1 more source
A case of melioidosis with hemoptysis: Strategies to isolate and identify Burkholderia pseudomallei
Background: Melioidosis is an infectious disease caused by Burkholderia pseudomallei with diverse clinical manifestations. Mortality is due to septic shock and pneumonia. Burkholderia pseudomallei is a Gram-negative rod with bipolar staining. Culture is
Therese Mary Dhason +5 more
doaj +1 more source

