Results 41 to 50 of about 12,860 (175)
Characterization of Burkholderia pseudomallei and Burkholderia pseudomallei-like strains
Previous reports in the literature suggest that Burkholderia pseudomallei strains can be differentiated on the basis of animal virulence. Twenty environmentally and clinically derived isolates of Burkholderia pseudomallei were examined for the production of exoenzymes, morphological and biochemical phenotypes and virulence for Syrian ...
P J, Brett, D, Deshazer, D E, Woods
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Burkholderia pseudomallei transcriptional adaptation in macrophages [PDF]
Abstract Background Burkholderia pseudomallei is a facultative intracellular pathogen of phagocytic and non-phagocytic cells. How the bacterium interacts with host macrophage cells is still not well understood and is critical to appreciate the strategies used by this bacterium to survive and how ...
Sylvia Chieng +2 more
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Bacterial persistence due to antibiotic tolerance is a critical aspect of antibiotic treatment failure, disease latency, and chronic or reemergent infections.
William Charles Nierman +2 more
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Computational Intelligence Accelerates CRISPR‐Cas‐Based Diagnostic Design
Computational intelligence, including pangenome‐guided target mining, machine‐learning‐based guide RNA optimization, and autonomous AI agents, is shifting CRISPR diagnostic design from empirical screening to systematic, data‐driven engineering and accelerating the path from pathogen discovery to deployable diagnostics.
Hengyu Wang +3 more
wiley +1 more source
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee +6 more
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Background Burkholderia are environmental bacteria mostly distributed in soil and water. Species of these bacteria can cause melioidosis in humans and animals, as well as necrotizing pneumonia in patients with cystic fibrosis.
Alabi Peter Dare +7 more
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Background Burkholderia pseudomallei is the bacterial causative agent of melioidosis, a difficult disease to diagnose clinically with high mortality if not appropriately treated. Definitive diagnosis requires isolation and identification of the organism.
Wanitda Watthanaworawit +15 more
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ABSTRACT Rapid and sensitive detection of disease‐related biomarkers is critical for early diagnosis and appropriate treatment. However, conventional analytical methods are often time‐consuming and require complex procedures and skilled personnel.
Minju Ahn +4 more
wiley +1 more source
Molecular phylogeny of Burkholderia pseudomallei
In terms of population structure, the species Burkholderia pseudomallei contains both clonal and non-clonal elements. By indexing variation in rRNA loci using the restriction endonuclease BamHI, we found that two ribotypes (types 1 and 3) are predominant in nature. Ribotype 3 is prevalent in Asian countries while ribotype 1 is more widespread.
Pitt, T, Trakulsomboon, S, Dance, D
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BIOFILMS OF PATHOGENIC BURKHOLDERIA AND THEIR ROLE IN RESISTANCE TO ANTIBIOTICS
The review contains the current knowledge on the main issues of Burkholderia pseudomallei and Burkholderia mallei biofilm formation. The role ofknown structural elements of Burkholderia cells (flagella, type IV pili, LPS), as well as autotransporter ...
E. V. Shubnikova +4 more
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