Results 41 to 50 of about 16,054 (178)

Role of RelA and SpoT in Burkholderia pseudomallei Virulence and Immunity [PDF]

open access: yes, 2012
Burkholderia pseudomallei is a Gram-negative soil bacterium and the causative agent of melioidosis, a disease of humans and animals. It is also listed as a category B bioterrorism threat agent by the U.S.
Wand, ME   +11 more
core   +1 more source

In silico analyses of penicillin binding proteins in Burkholderia pseudomallei uncovers SNPs with utility for phylogeography, species differentiation, and sequence typing.

open access: yesPLoS Neglected Tropical Diseases, 2022
Burkholderia pseudomallei causes melioidosis. Sequence typing this pathogen can reveal geographical origin and uncover epidemiological associations. Here, we describe B.
Heather P McLaughlin   +2 more
doaj   +1 more source

Phenotypic and Functional Characterization of Human Memory T Cell Responses to Burkholderia pseudomallei [PDF]

open access: yes, 2009
Copyright: © 2009 Tippayawat et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Direk Limmathurotsakul   +40 more
core   +1 more source

T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis. [PDF]

open access: yes, 2015
There is an urgent need for a better understanding of adaptive immunity to Burkholderia pseudomallei, the causative agent of melioidosis that is frequently associated with sepsis or death in patients in Southeast Asia and Northern Australia.
Sumonwiriya, M   +41 more
core   +1 more source

An unusual case of primary melioidotic prostatic abscess complicated by perianal abscess

open access: yesIDCases, 2018
Burkholderia pseudomallei is recognized to cause severe and fatal infections. Most of the infections caused by this facultative intracellular gram-negative bacterium are pneumonia, soft tissue, genito-urinary and central nervous system infection.
Y.C. Chee, Y.N. Chee
doaj   +1 more source

Efflux Pump-mediated Drug Resistance in Burkholderia

open access: yesFrontiers in Microbiology, 2015
Several members of the genus Burkholderia are prominent pathogens. Infections caused by these bacteria are difficult to treat because of significant antibiotic resistance.
Nicole L Podnecky   +4 more
doaj   +1 more source

Diverse Burkholderia Species Isolated from Soils in the Southern United States with No Evidence of B. pseudomallei. [PDF]

open access: yesPLoS ONE, 2015
The global distribution of the soil-dwelling bacterium Burkholderia pseudomallei, causative agent of melioidosis, is poorly understood. We used established culturing methods developed for B.
Carina M Hall   +11 more
doaj   +1 more source

Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy [PDF]

open access: yes, 2014
Whole-genome sequencing of the four isolates used in this study was supported by Wellcome Trust grant 098051, awarded to the Wellcome Trust Sanger Institute.
Theobald, V   +38 more
core   +1 more source

Human immune responses to Burkholderia pseudomallei characterized by protein microarray analysis.

open access: yes, 2011
BACKGROUND: We aimed to determine the antibody and T cell responses to Burkholderia pseudomallei of humans to select candidate vaccine antigens. METHODS: For antibody profiling, a protein microarray of 154 B.
Richard W. Titball   +26 more
core   +1 more source

Glyburide reduces bacterial dissemination in a mouse model of melioidosis [PDF]

open access: yes, 2013
Background: Burkholderia pseudomallei infection (melioidosis) is an important cause of community-acquired Gram-negative sepsis in Northeast Thailand, where it is associated with a ,40% mortality rate despite antimicrobial chemotherapy. We showed in a
Krause, Kathrin   +55 more
core   +1 more source

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