Results 111 to 120 of about 8,113 (274)

Ultrasound‐Responsive Dual‐Prodrug Nanoassembly for “Fenestrae‐Restoration Strategy” in Liver Fibrosis Therapy

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Liver fibrosis is a serious yet reversible intermediate stage in the progression of liver disease, which can ultimately advance to cirrhosis and hepatocellular carcinoma. Targeted and selective inhibition of activated hepatic stellate cells (aHSCs) has emerged as a promising therapeutic strategy for the treatment of liver fibrosis.
Shutong Liu   +8 more
wiley   +1 more source

EFFECTIVENESS OF A TEST-SVSTEM FOR DIAGNOSTICS OF MELIOIDOSIS AND GLANDERS BASED ON PASSIVE HEMAGGLUTINATION REACTION AND SOLID-PHASE ENZYME IMMUNOASSAY

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2016
Analysis of published results of studies of effect of various antigens of Burkholderia pseudomallei and B. mallei on operation characteristics (sensitivity and specificity) of tests for diagnostics of melioidosis and glanders based on reaction of passive
A. A. Budchenko
doaj   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

open access: yesAdvanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee   +21 more
wiley   +1 more source

Hydro‐Torsional Compaction for Scalable Production of Aramid Nanofiber Threads with Densely Assembled Double‐Helical Nanostructures

open access: yesAdvanced Materials, EarlyView.
This paper introduces a scalable strategy for producing hierarchically aligned PBDT threads through wet‐spinning, controlled drawing, and post‐spinning twisting. Ionic crosslinking reinforces structural stability, whereas alignment and twisting optimize mechanical performance.
Woojae Jeong   +5 more
wiley   +1 more source

The Historical Development of Animal Toxicity Testing [PDF]

open access: yes, 2012
This paper traces the historical development of animal toxicity testing, from its ancient origins through the period of standardization following World War II.
Gertler, N.
core  

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

open access: yesAdvanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez   +17 more
wiley   +1 more source

The pathogen Pseudomonas aeruginosa negatively affects the attraction response of the nematode Caenorhabditis elegans to bacteria.

open access: yes, 2006
The nematode Caenorhabditis elegans has previously been used to identify virulence mechanisms of bacteria and to characterise host responses to infection. In this study, we have developed an assay to measure C.
Atkins, Helen S   +3 more
core   +1 more source

Electrochemically Engineered PEDOT:PSS/MXene Composite Electrode for the Label‐Free Procalcitonin Detection

open access: yesAdvanced Materials Interfaces, EarlyView.
Procalcitonin is a key biomarker for bacterial infections, but conventional detection methods are often time‐consuming. Here, we present an electrochemical sensor based on highly conductive Ti3C2Tx MXene combined with PEDOT:PSS, enabling direct antibody immobilization, while a bovine serum albumin coating provides antifouling protection.
Angelika Banaś   +6 more
wiley   +1 more source

Absence of Yersinia pestis-specific DNA in human teeth from five European excavations of putative plague victims.

open access: yes, 2004
This study reports the results of a collaborative study undertaken by two independent research groups to (a) confirm recent PCR-based detection of Yersinia pestis DNA in human teeth from medieval plague victims in France, and (b) to extend these ...
Cooper, Alan   +6 more
core   +1 more source

Fabrication Technologies for Soft, Multimaterial Optical Fibers for In Vivo Diagnostics and Phototherapy, With a Focus on Extrusion Printing

open access: yesAdvanced Materials Technologies, EarlyView.
Soft multimaterial optical fibers integrate multiple functionalities—such as waveguiding, side emission, sensing, drug delivery or actuation—into a single filament for wearable, implantable, and tissue‐integrated devices for diagnostics and phototherapy.
Zahra Kafrashian   +2 more
wiley   +1 more source

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