Legacy and impact of the 1925 Geneva Protocol: one hundred years of treaties and debates on chemical and biological weapons. [PDF]
Front MicrobiolGrunden WE, Tuovinen OH.
europepmc +1 more source
Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects
Animal Models and Experimental Medicine, EarlyView.Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu +12 more
wiley +1 more source
An evaluation of antibiotic options for the treatment of biothreat pathogens. [PDF]
Front AntibiotMeinig JM +4 more
europepmc +1 more source
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model
Annals of Neurology, EarlyView.Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins +104 more
wiley +1 more source
Angewandte Chemie, EarlyView.A two‐nanosensor electrochemical strategy quantitatively distinguishes reactive oxygen species (ROS) in stress granules (SGs) from catecholamines in vesicles inside living cells. Chronic SGs formed under prolonged stress show elevated ROS and slower release, consistent with SG aging, and promote neurotransmitter loading likely through vesicle fusion ...
Hui Gu +3 more
wiley +2 more sources
Isolation of Burkholderia pseudomallei from a goat in New Caledonia: implications for animal and human health monitoring and serological tool comparison. [PDF]
BMC Vet ResDesoutter A +9 more
europepmc +1 more source
Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment
Advanced NanoBiomed Research, EarlyView.Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang +7 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen +10 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola
The Anatomical Record, EarlyView.Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum +3 more
wiley +1 more source