Necropsy findings as a post mortem diagnostic technique for transmissible diseases [PDF]
Zoonoses are considered as diseases transmissible between human and animal and can cause severe reactions in humans, leading to high death. To date, significant effort has been made in the prevention and treatment of zoonotic diseases.
Masoumeh Moradi-Ozarlou, +1 more
doaj +1 more source
Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. [PDF]
UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its ...
Atkins +34 more
core +3 more sources
Prevalence-dependent use of serological tests for diagnosing glanders in horses
Background The internationally mandatory complement fixation test (CFT) for testing of equine sera for the absence of glanders has repeatedly led to discrepant results. Not only do "false positive" sera pose a problem for the diagnostician and the animal
Scholz Holger C +6 more
doaj +1 more source
Outer Membrane Vesicle Vaccines from Biosafe Surrogates Prevent Acute Lethal Glanders in Mice
Burkholderia mallei is a host-adapted Gram-negative mammalian pathogen that causes the severe disease glanders. Glanders can manifest as a rapid acute progression or a chronic debilitating syndrome primarily affecting solipeds and humans in close ...
Michael H. Norris +4 more
doaj +1 more source
Glanders: re-emergence of an ancient zoonosis [PDF]
Glanders, although known to be endemic in certain regions/countries of the Old and New Worlds for centuries, had been largely overlooked as a threat to equine and human health until the disease re-emerged in the Middle East in 2004.
Patricia Ellis
doaj
The identification of causative agents of dangerous infectious diseases of bacterial origin is one of the main tasks of the biological protection of troops and the civilian population of the Russian Federation. This article is dedicated to the problem of
A. S. Tumanov +9 more
doaj +1 more source
MELIOIDOSIS AND GLANDERS: CURRENT STATE AND ACTUAL ISSUES OF EPIDEMIOLOGICAL SURVEILLANCE
Burkholderia pseudomallei and Burkholderia mallei are etiologic agents of glanders and melioidosis, the particularly dangerous infections of animals and humans, and are attributed to potential agents of bioterrorism.
I. B. Zakharova +2 more
doaj +1 more source
Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial Cells [PDF]
Members of the Burkholderia species can cause a range of severe, often fatal, respiratory diseases. A variety of in vitro models of infection have been developed in an attempt to elucidate the mechanism by which Burkholderia spp.
Graeme C. Clark +2 more
core +1 more source
Natural Burkholderia mallei Infection in Dromedary, Bahrain
We confirm a natural infection of dromedaries with glanders. Multilocus variable number tandem repeat analysis of a Burkholderia mallei strain isolated from a diseased dromedary in Bahrain revealed close genetic proximity to strain Dubai 7, which caused ...
Ulrich Wernery +10 more
doaj +1 more source
Effectiveness of an antimicrobial treatment scheme in a confined glanders outbreak [PDF]
BACKGROUND: Glanders is a contagious and fatal zoonotic disease of solipeds caused by the Gram-negative bacterium Burkholderia (B.) mallei. Although regulations call for culling of diseased animals, certain situations e.g.
Abeera Naureen +9 more
core +1 more source

