Results 111 to 120 of about 22,866 (307)

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

open access: yesAdvanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian   +9 more
wiley   +1 more source

Anti-Glare Filters

open access: yes, 1989
Glare from CRT screens has been blamed for blurred vision, eyestrain, headaches, etc. Optical Coating Laboratory, Inc. (OCLI) manufactures a coating to reduce glare which was used to coat the windows on the Gemini and Apollo spacecraft. In addition, OCLI

core  

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

open access: yesAdvanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu   +13 more
wiley   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

open access: yesAdvanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang   +10 more
wiley   +1 more source

A PRELIMINARY STUDY ON VEGETATIVE SHADING TO MINIMISE GLARE

open access: yesDimensi: Journal of Architecture and Built Environment, 2004
In low cost housing of warm humid regions where natural ventilation is usually employed, the presence of large openings will also cause unnecessary glare and heat gain of solar radiation This paper reports a preliminary study to handle glare issue ...
Christina E. Mediastika   +1 more
doaj  

Dynamic Reconstruction‐Engineered Heterointerfaces for Acidic Hydrogen Evolution at Ampere‐Level Current Density

open access: yesAdvanced Science, EarlyView.
A dynamic reconstruction strategy was utilized to construct PtCu/Cu3P heterostructures on the surface of self‐supporting Cu3P nanowires. The loose porosity in the restructured layer, together with a dynamic “dissolution‐redeposition” equilibrium during electrocatalysis, enables the electrode to maintain a low, stable overpotential for 240 h at ampere ...
Kaixi Wang   +3 more
wiley   +1 more source

Efficient Glare Suppression Network for Nighttime Images with Lightweight Parallel Attention and Ghost Convolution

open access: yesSensors
Aiming at the problems of glare interference, local overexposure and detail loss caused by artificial light sources such as vehicle lamps and street lamps in nighttime road scenes, as well as the challenges of existing glare suppression models with large
Ruoyu Yang   +3 more
doaj   +1 more source

Headlight Glare Resistance and Driver Age

open access: yes, 1980
The physiological glare thresholds (defined as the logarithm of the ratio at threshold between illuminances of glare source and target background) of 148 subjects from 5 to 91 years of age were measured in a Wolf glare tester.
Ernst Wolf   +4 more
core   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng   +7 more
wiley   +1 more source

Discomfort glare from daylighting: study of factors influencing discomfort glare perception and validation of a universal discomfort glare index

open access: yes, 2017
Nowadays, no current index can properly explain the high variability existing between individuals’ discomfort glare perception. The mechanism behind the discomfort glare phenomenon is not well understood as some of the factors influencing this phenomenon
VELUX Daylight Symposium   +4 more
core  

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