Results 111 to 120 of about 27,407 (252)

Physiological responses in relation to glare: A case study in office setting

, 2018
The modern work setting is tailored to productivity, health, satisfaction, and comfort. A recognized factor that reduces productivity in workplaces is discomfort glare.
Hine, Trevor, Hamedani, Zahra, Solgi, Ebrahim, Isoardi, Gillian, Skates, Henry   +4 more
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USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

Anti-Glare Filters

, 1989
Glare from CRT screens has been blamed for blurred vision, eyestrain, headaches, etc. Optical Coating Laboratory, Inc. (OCLI) manufactures a coating to reduce glare which was used to coat the windows on the Gemini and Apollo spacecraft. In addition, OCLI

core  

Glare quantification for indoor volleyball

, 2018
Sports facilities all over the world apply LED lighting. The combination of high luminance and small luminous surfaces causes a high probability of glare and LED lighting contains these specifications.
Donners, Maurice, Rosemann, ALP Alexander, Rosemann, A.L.P., van Duijnhoven, J., Duijnhoven, J Juliette van, Donners, MAH Maurice, Pakkert, M, Pakkert, Martijn   +7 more
core   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

NRGS-Net: A Lightweight Uformer with Gated Positional and Local Context Attention for Nighttime Road Glare Suppression

Applied Sciences
Existing nighttime visibility enhancement methods primarily focus on improving overall brightness under low-light conditions. However, nighttime road images are also affected by glare, glow, and flare from complex light sources such as streetlights and ...
Ruoyu Yang, Huaixin Chen, Sijie Luo, Zhixi Wang   +3 more
doaj   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Discomfort glare from daylighting: study of factors influencing discomfort glare perception and validation of a universal discomfort glare index

, 2017
Nowadays, no current index can properly explain the high variability existing between individuals’ discomfort glare perception. The mechanism behind the discomfort glare phenomenon is not well understood as some of the factors influencing this phenomenon
VELUX Daylight Symposium, Pierson, Clotilde, Bodart, Magali, Cauwerts, Coralie, Wienold, Jan   +4 more
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