Results 91 to 100 of about 22,866 (307)
Measuring Chitinase and Protease Activity in Cultures of Fungal Entomopathogens
, 2016 Entomopathogenic fungi produce a variety of destructive enzymes and metabolites to overcome the unique defense mechanisms of insects. In a first step, fungal chitinases and proteinases need to break down the insect’s cuticle.
Michael Rostás +7 more
core +1 more source
Advanced Science, EarlyView.Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source
Nighttime driving in older adults: Effects of glare and association with mesopic visual function
, 2017 Purpose\ud \ud To examine the associations between nighttime driving performance of older drivers and photopic, mesopic, and glare-based tests of visual function.\ud \ud Methods\ud \ud Participants included 26 older drivers (71.8 ± 6.3 years), with ...
Wood, Joanne M. +5 more
core +1 more source
Advanced Science, EarlyView.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source
An Analysis and Simulation of Curtain Wall Reflection Glare
, 1999 This paper presents a computer-aided visualization on the influence of reflected sunbeams from curtain wall buildings. A survey was made to local buildings and it was discovered that reflected glare is a significant urban problem.
Y.S. Huang, N.J. Shih
core
Advanced Science, EarlyView.Tightly focused laser irradiation can accumulate tubulin proteins at/around the laser focus, which leads to the formation of highly ordered microtubule assemblies. The assemblies can exhibit various dynamic behaviors such as radial motion, bundling, and flagella‐like rotation with motor protein and chemical energy, highlighting as a unique tool for ...
Hiroshi Y. Yoshikawa +16 more
wiley +1 more source
A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates
Advanced Science, EarlyView.Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao +7 more
wiley +1 more source
Glare recovery and it's relation to other clinical\ud findings in age related maculopathy
, 1989 only\ud \ud Subjects in this stiudy were classified into one of three groups, age related maculopathy (ARM) pre-age related maculopathy (PARM) and age-matched contraols.
Brown, Brian, Collins, Michael J.
core
Temporal effects in glare response [PDF]
, 2016 Discomfort glare is considered to be an annoyance or distraction caused by sources of non-uniform or high luminance within the field of view of an observer.
Kent, Michael G.
core
Advanced Science, EarlyView.A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen +11 more
wiley +1 more source