Results 131 to 140 of about 126,567 (343)

Comparing performance of discomfort glare metrics in high and low adaptation levels

Building and Environment, 2021
G. Quek, J. Wienold, M. S. Khanie, E. Erell, E. Kaftan, Athanasios Tzempelikos, Iason Konstantzos, J. Christoffersen, Tilmann E. Kuhn, M. Andersen   +9 more
semanticscholar   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Regulation of Excitonic Behavior in Defective Acetylenic Polymers Enables Mechanism Switching in O2 Activation for Enhanced Water Decontamination

Advanced Science, EarlyView.
A molecular defect‐mediated charge accumulation strategy is developed to regulate the exciton behavior for selective molecular oxygen (O2)activation in poly(1,3,5‐triethynylbenzene) (PTEB). Artificial internal electric field (IEF) constructed in defective PTEB provides internal driving force to steer the directed migration of charge carriers, thereby ...
Xiaofeng Tang, Sijia Jin, Wei Li, Yingrong Wang, Haiyan Zhang, Zhiqiao He, Shuang Song, Yaqi Cai, Tao Zeng   +8 more
wiley   +1 more source

Constraints on Physical Properties of z~6 Galaxies Using Cosmological Hydrodynamic Simulations

, 2007
We conduct a detailed comparison of broad-band spectral energy distributions of six z >= 5.5 galaxies against galaxies drawn from cosmological hydrodynamic simulations.
Ajiki, Balogh, Benjamin D. Oppenheimer, Benítez, Berger, Bouwens, Bouwens, Bouwens, Bruzual, Bunker, Calzetti, Cardelli, Charlot, Chary, Cuby, Davé, Davé, Dawson, Dickinson, Drory, Dunlop, Egami, Erb, Eyles, Eyles, Fan, Fardal, Finlator, Gawiser, González-Serrano, Gordon, Gwyn, Haardt, Hu, Hu, Iben, Idzi, Kashikawa, Kauffmann, Kawai, Kennicutt, Keres, Kneib, Kodaira, Kolatt, Kristian Finlator, Kurk, Labbé, Madau, Malhotra, Malhotra, Maraston, Martin, McKee, Mobasher, Murray, Nagao, Nagao, Night, Oppenheimer, Ouchi, Papovich, Papovich, Rhoads, Rhoads, Rhoads, Romeel Davé, Rupke, Santos, Schaerer, Shapley, Shapley, Shimasaku, Smail, Somerville, Spergel, Spergel, Springel, Springel, Springel, Springel, Stanway, Stanway, Stanway, Stern, Stiavelli, Wang, Wang, Westra, Yan   +89 more
core   +3 more sources

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

An Enhanced NSGA-II Algorithm with Parameter Categorization for Computational-Efficient Multi-Objective Optimization of Active Glass Curtain Wall Shading Systems

Energies
To address the limitations of the Non-Dominated Sorting Genetic Algorithm (NSGA-II) in optimizing active glass curtain wall shading systems—particularly its suboptimal convergence efficiency and high computational demands—this study proposes an improved ...
Dezhao Tang, Zhiyong Wang
doaj   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Intertidal Warfare: Synergistic Allelopathy Mediates Spatial Competition between Two Marine Calcareous‐Shelled Sessile Organisms

Advanced Science, EarlyView.
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li, Zixin Huo, Shanshan Yao, Xianmeng Liang, Yiran Zhao, Yanxin Wang, Shifeng Guo, Caihuan Ke, Pei Su, Danqing Feng   +9 more
wiley   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source