Results 51 to 60 of about 669,450 (300)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Advanced Science, 2023 Revealing the critical thermodynamic parameters determining the glass formation of substances is of great significance for understanding the glass transition and guiding the composition design of glass‐forming materials.
Baokang Ren +4 more
doaj +1 more source
Thermodynamic limits of crystallization and the prediction of glass formation tendency [PDF]
, 2010 We have calculated the T0 curves for several Al-rare-earth binary alloys to assess the importance of the transport-based resistance to crystallization in the overall glass formation process and the general effectiveness of thermodynamic prediction of ...
Ho, Kai-Ming +4 more
core +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A new criterion for evaluating the glass-forming ability of bulk glass forming alloys [PDF]
Journal of Alloys and Compounds, 2008 Abstract Based on the classical theory of nucleation and growth, we propose a dimensionless criterion, β, expressed by TxTg/(Tl − Tx)2, with Tg, the glass transition temperature, Tx, the onset of crystallization temperature and Tl, the liquidus temperature for evaluating the glass-forming ability (GFA) of bulk metallic glasses (BMGs). A survey of the
Zi-Zhou Yuan +4 more
openaire +3 more sources
Glass-forming ability and soft magnetic properties of FeCoSiAlGaPCB amorphous alloys [PDF]
, 2002 The glass-forming ability of ( Fe x Co y B z C u ) 80 Si 3 Al 5 Ga 2 P 10 with x 5 5 – 70, y 5 0 – 63, z 5 5 – 12, and u 5 0 – 5 amorphous alloys has been analyzed in terms of the width of the supercooled liquid region, the
Borrego Moro, Josefa María +3 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Results in PhysicsThe impact of varying TeO2 content (0, 10, and 20 mol%) on the physical, optical, structural, and thermal properties was investigated for Eu2O3 doped borate glasses.
A. Khan +10 more
doaj +1 more source