KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The role of attractive forces in viscous liquids
, 2011 We present evidence from computer simulation that the slowdown of relaxation of a standard Lennard-Jones glass-forming liquid and that of its reduction to a model with truncated pair potentials without attractive tails is quantitatively and qualitatively
Gilles Tarjus +3 more
core +1 more source
Bioactivity of toothpaste containing bioactive glass in remineralizing media: effect of fluoride release from the enzymatic cleavage of monofluorophosphate [PDF]
, 2015 Objectives. The aim was to introduce a new methodology to characterize toothpaste containing bioactive glass and to evaluate the effect of release of fluoride ions, by cleaving monofluorophosphate (MFP), on the mineral forming ability of Sensodyne Repair
Earl, JS +3 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Relation of Structure, Composition and Glass Forming Ability in Zr-Cu Binary Amorphous Alloys
MATEC Web of Conferences, 2016 Molecular dynamics simulation was used to simulate Zr-Cu binary system, in which the relationship between structure, composition and glass forming ability was study.
Dang Yizong, Wang Lu, Fan Qunbo
doaj +1 more source
Role of bioglass derivatives in tissue regeneration and repair: A review
Reviews on Advanced Materials Science, 2023 Bioceramics are significantly contributing in repairing and reconstructing the defective areas of the musculoskeletal system. Bioactive glass is a non-crystalline bioceramic that has been widely used in regeneration due to its extensive bone-forming ...
Gao Yang +2 more
doaj +1 more source
Composition Dependence of Glass Forming Propensity in Al−Ni Alloys [PDF]
, 2011 Enormous progress has been made over the past decade in developing bulk amorphous alloys with high strength and other mechanical properties while possessing improved glass forming and processing abilities. Particularly important in developing new systems
An, Qi +2 more
core +1 more source
Zr and Hf microalloying in an Al-Y-Fe amorphous alloy. Relation between local structure and glass-forming ability [PDF]
, 2008 International audienceThe effects of the addition of small amounts of Zr and Hf (0.5 - 3 %) on the atomic structure of Al88Y7Fe5 metallic glass were examined from extended x-ray absorption fine structure (EXAFS) experiments to better understand the ...
Hazemann, Jean-Louis +5 more
core +3 more sources
Can glass stability parameters infer glass forming ability? [PDF]
Journal of Non-Crystalline Solids, 2005 Glass-forming ability (GFA) is the easiness to vitrify a liquid on cooling, while glass stability (GS) is the glass resistance against devitrification on heating; but it is questionable if there is any direct relationship between these two parameters.
Marcio L.F. Nascimento +3 more
openaire +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source