Results 51 to 60 of about 21,105,669 (168)
Anti-inflammatory effects of glaucocalyxin B in microglia cells
Journal of Pharmacological Sciences, 2015 Over-activated microglia is involved in various kinds of neurodegenerative process including Parkinson, Alzheimer and HIV dementia. Suppression of microglial over activation has emerged as a novel strategy for treatment of neuroinflammation-based ...
Ping Gan +10 more
doaj +1 more source
Small molecule inhibitors of osteoarthritis: Current development and future perspective [PDF]
, 2023 Osteoarthritis (OA) is one of the common degenerative joint diseases in clinic. It mainly damages articular cartilage, causing pain, swelling and stiffness around joints, and is the main cause of disability of the elderly. Due to the unclear pathogenesis
Bin Hu +7 more
core +1 more source
Nrf2 Pathway in Age-Related Neurological Disorders: Insights into MicroRNAs [PDF]
, 2018 A general hallmark of neurological diseases is the loss of redox homeostasis that triggers oxidative damages to biomolecules compromising neuronal function.
Andrea Conte +4 more
core +2 more sources
Glaucocalyxin A Ameliorates Myocardial Ischemia-Reperfusion Injury in Mice by Suppression of Microvascular Thrombosis [PDF]
Medical Science Monitor, 2016 BACKGROUND The aim of this study was to evaluate the cardio-protective roles of glaucocalyxin A (GLA) in myocardial ischemia-reperfusion injury and to explore the underlying mechanism. MATERIAL AND METHODS Myocardial ischemia-reperfusion in wild-type C57BL/6J mice was induced by transient ligation of the left anterior descending artery. GLA or vehicle (
Liu, Xiaohui +7 more
openaire +2 more sources
Review Article Natural Products for Antithrombosis [PDF]
, 2020 Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on
Cen Chen +5 more
core
Development of novel herbal compound combinations targeting neuroinflammation : network pharmacology, molecular docking and experimental verification [PDF]
, 2023 This study aimed to develop a novel herbal compound combination to attenuate neuroinflammation with a synergistic approach in vitro. Two novel herbal compound combinations targeting neuroinflammation with a synergistic approach have been identified ...
Liu, Yang
core +1 more source
Glaucocalyxin A inhibits the growth of liver cancer Focus and SMMC-7721 cells
Oncology Letters, 2015 Liver cancer is one of the most common types of cancer, and hepatoma demonstrates a poor long-term prognosis. The present study reports that glaucocalyxin A (GLA), a natural product isolated from Rabdosia umbrosa, inhibits the growth of the liver cancer Focus and SMMC-7721 cell lines in a dose- and time-dependent manner. The present study revealed that
Lisha, Tang +5 more
openaire +3 more sources
Chinese Medicines for Cancer Treatment from the Metabolomics Perspective [PDF]
, 2019 Cancer is one of the most prevalent diseases all over the world with poor prognosis and the development of novel therapeutic strategies is still urgently needed.
Feng, Yibin +3 more
core +1 more source
Natural Products for Antithrombosis
Evidence-Based Complementary and Alternative Medicine, Volume 2015, Issue 1, 2015., 2015 Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and cellular basis of thrombus formation as well as ...
Cen Chen +6 more
wiley +1 more source
International Journal on Biological Sciences, 2018 Glaucocalyxin A (GLA), a major component isolated from Rabdosia japonica, has been proven to show anti-bacterial and anti-tumor biological characteristics according to previous studies. However, its potential effect on bladder cancer remains unknown. The
Wenfeng Lin +10 more
semanticscholar +1 more source