Results 1 to 10 of about 116,427 (215)

Effect of antioxidants on primary open-angle glaucoma: a systematic review and meta-analysis [PDF]

Frontiers in Pharmacology
Background/ObjectivesPrimary open-angle glaucoma is a major global cause of vision loss, severely impacting quality of life. Although the need for effective treatments is widely recognized, the efficacy and safety of antioxidants remain uncertain.
Jie Bao, Yujia Yu, Guosen Chen, Chen Hu, Cong Zhao, Xiang Li   +5 more
doaj   +2 more sources

Effect of Glaucoma on Corneal Endothelium [PDF]

Egyptian Journal of Medical Research, 2021
Background: Glaucoma is a group of diseases characterized by a specific pattern of optic nerve neuropathy and retinopathy which is permenant. There is increasing evidence of glaucoma-associated corneal endothelial changes.
Hazem Effat Abd El-Ghany Mohammad Haroon, Asmaa Mohamed Samir, Haytham Ibrahim Ibrahim El-Shawaf, Muller Victor Shaker   +3 more
doaj   +1 more source

MYOC Gene Sequencing Analysis in Primary Open-Angle Glaucoma Patients from the Centre Region of Portugal

Acta Médica Portuguesa, 2021
Introduction: Primary open-angle glaucoma is the most frequent subtype of glaucoma. Relatives of primary open-angle glaucoma patients have an increased risk of developing the disease, suggesting a genetic predisposition to the disease.
Filipe Silva, Filipa Ferreira, Pedro Faria, Isa Sobral, Mariana Rodrigues, João Pratas, João Filipe Silva, Manuela Grazina, José Moura Pereira, Henrique Girão, Paulo Pereira   +10 more
doaj   +1 more source

Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review

Scientific Reports, 2021
Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness in the world and is influenced by various sociodemographic factors. This meta-analysis aims to determine the worldwide prevalence of POAG in the adult general population for ...
Nan Zhang, Jiaxing Wang, Ying Li, B. Jiang   +3 more
semanticscholar   +1 more source

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Nature Communications, 2021
Primary open-angle glaucoma (POAG), is a heritable common cause of blindness world-wide. To identify risk loci, we conduct a large multi-ethnic meta-analysis of genome-wide association studies on a total of 34,179 cases and 349,321 controls, identifying ...
P. Gharahkhani, E. Jorgenson, P. Hysi, A. Khawaja, S. Pendergrass, Xikun Han, Jue-Sheng Ong, A. Hewitt, A. Segrè, J. Rouhana, Andrew R. Hamel, R. Igo, H. Choquet, Ayub Qassim, N. Josyula, J. C. Cooke Bailey, Pieter W. M. Bonnemaijer, Adriana I. Iglesias, O. Siggs, T. Young, V. Vitart, A. Thiadens, J. Karjalainen, S. Uebe, R. Melles, K. S. Nair, R. Luben, Mark J. Simcoe, Nishani Amersinghe, A. Cree, Rene Hohn, A. Poplawski, L. J. Chen, S. Rong, T. Aung, E. Vithana, G. Tamiya, Yukihiro Shiga, Masayuki Yamamoto, T. Nakazawa, Hannah Currant, E. Birney, Xin Wang, A. Auton, Michelle K. Lupton, N. Martin, A. Ashaye, O. Olawoye, S. Williams, S. Akafo, M. Ramsay, Kazuki Hashimoto, Y. Kamatani, M. Akiyama, Y. Momozawa, P. Foster, P. Khaw, J. Morgan, N. Strouthidis, P. Kraft, J. Kang, C. Pang, F. Pasutto, P. Mitchell, A. Lotery, A. Palotie, C. V. van Duijn, J. Haines, C. Hammond, L. Pasquale, C. Klaver, M. Hauser, C. Khor, D. Mackey, M. Kubo, Ching-Yu Cheng, J. Craig, S. Macgregor, J. Wiggs   +78 more
semanticscholar   +1 more source

PreserFlo® MicroShunt: An Overview of This Minimally Invasive Device for Open-Angle Glaucoma

Vision, 2022
For moderate-to-severe glaucoma, trabeculectomy remains the “gold standard” intraocular pressure (IOP)-lowering treatment; nonetheless, this method requires extensive post-operative maintenance.
G. Gambini, Matteo Mario Carlà, Federico Giannuzzi, T. Caporossi, Umberto De Vico, A. Savastano, A. Baldascino, Clara Rizzo, Raphael Kilian, A. Caporossi, S. Rizzo   +10 more
semanticscholar   +1 more source

Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.

JAMA ophthalmology, 2021
Importance Open-angle glaucoma may continue to progress despite significant lowering of intraocular pressure (IOP). Preclinical research has suggested that enhancing mitochondrial function and energy production may enhance retinal ganglion cell survival ...
C. D. De Moraes, S. John, Pete A. Williams, D. Blumberg, G. Cioffi, J. Liebmann   +5 more
semanticscholar   +1 more source

Comparison of visual field progression in new-diagnosed primary open-angle and exfoliation glaucoma patients in Sweden

BMC Ophthalmology, 2020
Background The present study aimed to compare visual field progression in new-diagnosed exfoliation versus open-angle glaucoma patients. Methods Retrospective study.
Marcelo Ayala
doaj   +1 more source

Racial and Ethnic Disparities in Primary Open-Angle Glaucoma Clinical Trials

JAMA Network Open, 2021
Key Points Question What is the prevalence of participants from racial/ethnic minority groups compared with White individuals in primary open-angle glaucoma (POAG) clinical trials? Findings In this meta-analysis of 33 428 POAG clinical trial participants,
Karen Allison, Deepkumar Patel, Leah Greene   +2 more
semanticscholar   +1 more source

The prevalence of diabetes among male glaucoma patients

The Pan-American Journal of Ophthalmology, 2020
Introduction: The purpose of this study was to examine the relationship between diabetes and glaucoma. Methods: Consecutive 143 subjects with primary angle-closure glaucoma and 127 subjects with primary open-angle glaucoma (control) were studied ...
Nataliya Antonova, Inci Irak Dersu, Eitan Burstein, Lance Lyons, Wei Hou   +4 more
doaj   +1 more source