Results 71 to 80 of about 112,057 (268)

Endocrine Dysfunction in Open Angle Glaucoma

open access: yesKlinische Monatsblätter für Augenheilkunde, 2021
AbstractThe eye, like all organs, is exposed to the effects of the bodyʼs endocrine system. In addition, however, local branches of the endocrine system control important organ-specific functions, such as the production and drainage of aqueous humour.
openaire   +4 more sources

The genetics of primary open angle glaucoma [PDF]

open access: yesBritish Journal of Ophthalmology, 1997
The advent of the discipline of molecular genetics over the past decade has led to a dramatic growth in our understanding of the genetics of a myriad of diseases. Ophthalmology has benefited greatly from this new technology, with significant advances in our knowledge about conditions as varied as aniridia and retinitis pigmentosa.1 2 Our understanding ...
Amanda J. Churchill   +4 more
openaire   +3 more sources

Role of Fibronectin in Primary Open Angle Glaucoma

open access: yesCells, 2019
Primary open angle glaucoma (POAG) is the most common form of glaucoma and the 2nd most common cause of irreversible vision loss in the United States. Nearly 67 million people have the disease worldwide including >3 million in the United States.
Jennifer A. Faralli   +2 more
semanticscholar   +1 more source

Risk of open angle glaucoma due to tumor necrosis factor alpha gene polymorphisms

open access: yesElectronic Physician, 2016
Introduction: Axonal degeneration and retinal ganglion cell apoptosis in glaucoma is associated with tumor necrosis factor alpha (TNF-α), which is an important pro-inflammatory cytokine.
Mona Abdel Hamid   +4 more
doaj   +1 more source

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations of African ancestry compared with European or Asian ancestry.
M. Hauser   +92 more
semanticscholar   +1 more source

Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model

open access: yesMacromolecular Bioscience, EarlyView.
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz   +6 more
wiley   +1 more source

Attention Based Glaucoma Detection: A Large-scale Database and CNN Model [PDF]

open access: yesarXiv, 2019
Recently, the attention mechanism has been successfully applied in convolutional neural networks (CNNs), significantly boosting the performance of many computer vision tasks. Unfortunately, few medical image recognition approaches incorporate the attention mechanism in the CNNs.
arxiv  

Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration

open access: yesScientific Reports, 2016
Primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD) are leading causes of irreversible blindness. Several loci have been mapped using genome-wide association studies.
G. Cuéllar-Partida   +13 more
semanticscholar   +1 more source

Modeling fire‐related smoke inhalation injury using the human lung‐on‐a‐chip and organoid platform: Pathogenesis insights and therapeutic evaluation

open access: yesVIEW, EarlyView.
Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li   +12 more
wiley   +1 more source

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