Results 91 to 100 of about 181,538 (267)

Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort

BMC Research Notes, 2018
Objective Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye.
Altaf A. Kondkar, Tahira Sultan, Faisal A. Almobarak, Hatem Kalantan, Khaled K. Abu-Amero, Saleh A. Al-Obeidan   +5 more
doaj   +1 more source

Development of an Efficient and Scalable Process for Preparing Timolol N‐Nitrosamine Impurities B, C, E, H, I, J, and Their ADMET Evaluation

Journal of Heterocyclic Chemistry, EarlyView.
N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad, Chithaluri Sudhakar, Vijaya Krishna Ravi, Bijaya Kethan Sahoo   +3 more
wiley   +1 more source

Comparative Evaluation of Four Stereotactic Radiosurgery Planning Approaches for Treatment of Posterior Choroidal Melanoma

Journal of Medical Radiation Sciences, EarlyView.
This study evaluated four stereotactic radiosurgery planning approaches for posterior choroidal melanoma (CM). Analysis of thirteen CM cases resulted in a clinically meaningful reduction in dose to the brain for Brainlab Elements modulated arcs (BE) and Varian Eclipse HyperArc modulated arcs (HA) compared to Brainlab iPlan dynamic conformal arc therapy
Robert Nigro, Kenton Thompson, Cathy Markham, Adam U. Yeo, Daniel Sapkaroski, Claire Phillips   +5 more
wiley   +1 more source

Morphology of corneal nerves using Confocal Microscopy ( Confoscan 3) in the open angle glaucoma”

, 2005
Morphology of corneal nerves using Confocal Microscopy ( Confoscan 3) in the open angle ...
DONATI S., ARRICO, Loredana, PUCCI R, ACCONCIA M.C., MASCARO T.   +4 more
core  

Shortened outreach periodontal therapy in nursing home residents with periodontitis: A randomized controlled trial

Journal of Periodontology, EarlyView.
Abstract Background We examined the clinical effectiveness of shortened outreach periodontal therapy for 3 months in nursing home residents with periodontitis versus controls (no therapy). Methods Nursing home residents with periodontitis were randomly assigned to either (a) one‐time, shortened outreach periodontal therapy adapted to German statutory ...
Anna G. Barbe, Dalia Beck, Martin Hellmich, Max von Kohout, Sonja H. M. Derman, Dirk Bleiel   +5 more
wiley   +1 more source

One-Year Outcomes of Second-Generation Trabecular Micro-Bypass Stents (iStent Inject) Implantation with Cataract Surgery in Different Glaucoma Subtypes and Severities

Ophthalmology and Therapy, 2019
Purpose To assess the 1-year efficacy and safety of the implantation of two second-generation trabecular micro-bypass stents (iStent Inject®) with concomitant cataract surgery in various subtypes and severities of glaucoma.
Ali Salimi, Julie Lapointe, Paul Harasymowycz   +2 more
doaj   +1 more source

Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma

, 2008
Purpose: To evaluate genetic susceptibility of lysyl oxidase-like 1 (LOXL1) gene polymorphisms to exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) in a case-control cohort of American and European patients.
Spiteri, Anthony, Tarkkanen, A, Sarfarazi, M, O\u27Brien, Colm, Ritch, Robert, Tarkkanen, Ahti, Child, AH, Aragon-Martin, JA, Spiteri, A, Liebmann, Jeffrey, Liebmann, J, Cobb, CJ, Blaaow, Karima, Mercieca, Franco, Mercieca, F, Damji, KF, O'Brien, C, Blaaow, K, Rezaie, T, Cobb, Caroline J, Damji, Karim F, Ritch, R, Aragon-Martin, Jose A   +22 more
core  

A genome-wide association study of intra-ocular pressure suggests a novel association in the gene FAM125B in the TwinsUK cohort

, 2014
Glaucoma is a major cause of blindness in the world. To date, common genetic variants associated with glaucoma only explain a small proportion of its heritability. We performed a genome-wide association study of intra-ocular pressure (IOP), an underlying
Aung, T., van Koolwijk, L.M., Tanja, Z., Khor, C.-C., Venturini, C., Mackey, D.A., Jonas, J.B., Hammond, C., Vitart, V., Viswanathan, A.C., Hewitt, A.W., Gibson, J., Klaver, C.C., Nag, A., WTCCC, None, Xu, L., Lemij, H.G., Liao, J., Wang, J.J., Mitchell, P., Young, T. L., Macgregor, S., Ramdas, W.D., Vithana, E., Hofman, A., Lu, Y., Small, K.S., Wojciechowski, R., van Duijn, C.M., Hysi, P.G., Springelkamp, H., Yonova-Doing, E., Fleck, B.W., Williams, K.M., Wong, T.-Y., Uitterlinden, A.G., Lotery, A.J., Cheng, C.-Y., Tai, E.-S., Hohn, R., Teo, Y.-Y., Vingerling, J.R.   +41 more
core   +1 more source

Assessment of Treatment Response in Patients With Scleromyxedema by the Double Modified Rodnan Skin Score

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Scleromyxedema (SMX) is a cutaneous mucinosis characterised by an abnormal accumulation of mucin in the skin and limited treatment options. Assessment of therapy response during treatment is challenging. Objectives Patients with SMX receiving high‐dose intravenous IVIg therapy were included to assess validity of the double modified ...
Julia K. Winkler, Alexander H. Enk
wiley   +1 more source

Recalcitrant Eyelid Lupus Treated With Topical Ruxolitinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Lupus of the eyelids, or lupus blepharitis, is a rare and localized form of chronic cutaneous lupus. The use of topical corticosteroids is limited in this sensitive area due to the risk of adverse events. We present a case of eyelid lupus, with histological confirmation, resistant to multiple lines of treatment, successfully treated with ...
Clémence Bertold, Feriel Boukari, Valérie Elmaleh, Julia Bonnelye, Ulysse Jacquier, Nathalie Cardot‐Leccia, Thierry Passeron   +6 more
wiley   +1 more source